Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037150268> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2037150268 endingPage "29" @default.
- W2037150268 startingPage "25" @default.
- W2037150268 abstract "Patients with beta-thalassemia often present with a restrictive pattern at pulmonary function tests (PFTs) due to several pathogenetic factors. However, the long-term evolution is unknown. We performed a longitudinal study of pulmonary function in asymptomatic, non-smoking patients with beta-thalassemia major and intermedia. We looked for temporal changes in lung function and characteristics that would predict the development of PFT abnormalities. In 1996, 18 patients with major beta-thalassemia (9 males and 9 females; age range: 18-35 years) and 11 patients with intermediate beta-thalassemia (5 males and 6 females; age range: 25-51 years) underwent clinical assessment and PFT, including body plethysmography and gas transfer study (carbon monoxide diffusion capacity, DL(CO)). Patients were reassessed in 2003. An echocardiographic evaluation was also obtained to exclude pulmonary hypertension. In 55.5% of major and 45.4% of intermediate beta-thalassemia patients, a restrictive pattern was found in 1996; in 2003 only 38.8 and 27.2% of patients, respectively, exhibited total lung capacities below the predicted values. DL(CO) was unchanged in both groups of patients, being reduced in 5 thalassemia major patients and within the normal range in intermediate patients. We conclude that asymptomatic patients with beta-thalassemia have a high prevalence of PFT abnormalities, but without significant increases over time. An improvement may be observed when good control of the iron balance is reached with optimal chelation therapy." @default.
- W2037150268 created "2016-06-24" @default.
- W2037150268 creator A5035672495 @default.
- W2037150268 creator A5054484458 @default.
- W2037150268 creator A5061715659 @default.
- W2037150268 creator A5064506274 @default.
- W2037150268 creator A5071350316 @default.
- W2037150268 creator A5079239044 @default.
- W2037150268 date "2006-01-01" @default.
- W2037150268 modified "2023-10-16" @default.
- W2037150268 title "Lung Function in β-Thalassemia Patients: A Longitudinal Study" @default.
- W2037150268 cites W169140314 @default.
- W2037150268 cites W2021414189 @default.
- W2037150268 cites W2032250424 @default.
- W2037150268 cites W2037107259 @default.
- W2037150268 cites W2051003986 @default.
- W2037150268 cites W2056349132 @default.
- W2037150268 cites W2058347646 @default.
- W2037150268 cites W2082993664 @default.
- W2037150268 cites W2124219007 @default.
- W2037150268 cites W2165245938 @default.
- W2037150268 cites W3106356870 @default.
- W2037150268 doi "https://doi.org/10.1159/000092344" @default.
- W2037150268 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16809886" @default.
- W2037150268 hasPublicationYear "2006" @default.
- W2037150268 type Work @default.
- W2037150268 sameAs 2037150268 @default.
- W2037150268 citedByCount "29" @default.
- W2037150268 countsByYear W20371502682012 @default.
- W2037150268 countsByYear W20371502682013 @default.
- W2037150268 countsByYear W20371502682014 @default.
- W2037150268 countsByYear W20371502682016 @default.
- W2037150268 countsByYear W20371502682017 @default.
- W2037150268 countsByYear W20371502682019 @default.
- W2037150268 countsByYear W20371502682021 @default.
- W2037150268 countsByYear W20371502682022 @default.
- W2037150268 countsByYear W20371502682023 @default.
- W2037150268 crossrefType "journal-article" @default.
- W2037150268 hasAuthorship W2037150268A5035672495 @default.
- W2037150268 hasAuthorship W2037150268A5054484458 @default.
- W2037150268 hasAuthorship W2037150268A5061715659 @default.
- W2037150268 hasAuthorship W2037150268A5064506274 @default.
- W2037150268 hasAuthorship W2037150268A5071350316 @default.
- W2037150268 hasAuthorship W2037150268A5079239044 @default.
- W2037150268 hasConcept C126322002 @default.
- W2037150268 hasConcept C141071460 @default.
- W2037150268 hasConcept C164705383 @default.
- W2037150268 hasConcept C187212893 @default.
- W2037150268 hasConcept C27101514 @default.
- W2037150268 hasConcept C2777714996 @default.
- W2037150268 hasConcept C2777799968 @default.
- W2037150268 hasConcept C2777910003 @default.
- W2037150268 hasConcept C2777940137 @default.
- W2037150268 hasConcept C71924100 @default.
- W2037150268 hasConcept C75603125 @default.
- W2037150268 hasConcept C90924648 @default.
- W2037150268 hasConceptScore W2037150268C126322002 @default.
- W2037150268 hasConceptScore W2037150268C141071460 @default.
- W2037150268 hasConceptScore W2037150268C164705383 @default.
- W2037150268 hasConceptScore W2037150268C187212893 @default.
- W2037150268 hasConceptScore W2037150268C27101514 @default.
- W2037150268 hasConceptScore W2037150268C2777714996 @default.
- W2037150268 hasConceptScore W2037150268C2777799968 @default.
- W2037150268 hasConceptScore W2037150268C2777910003 @default.
- W2037150268 hasConceptScore W2037150268C2777940137 @default.
- W2037150268 hasConceptScore W2037150268C71924100 @default.
- W2037150268 hasConceptScore W2037150268C75603125 @default.
- W2037150268 hasConceptScore W2037150268C90924648 @default.
- W2037150268 hasIssue "1" @default.
- W2037150268 hasLocation W20371502681 @default.
- W2037150268 hasLocation W20371502682 @default.
- W2037150268 hasOpenAccess W2037150268 @default.
- W2037150268 hasPrimaryLocation W20371502681 @default.
- W2037150268 hasRelatedWork W1992877523 @default.
- W2037150268 hasRelatedWork W2048242646 @default.
- W2037150268 hasRelatedWork W2093247886 @default.
- W2037150268 hasRelatedWork W2104641455 @default.
- W2037150268 hasRelatedWork W2291513599 @default.
- W2037150268 hasRelatedWork W2382471307 @default.
- W2037150268 hasRelatedWork W2395461245 @default.
- W2037150268 hasRelatedWork W3007963219 @default.
- W2037150268 hasRelatedWork W3110033201 @default.
- W2037150268 hasRelatedWork W4382881400 @default.
- W2037150268 hasVolume "116" @default.
- W2037150268 isParatext "false" @default.
- W2037150268 isRetracted "false" @default.
- W2037150268 magId "2037150268" @default.
- W2037150268 workType "article" @default.