Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037156739> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2037156739 endingPage "179" @default.
- W2037156739 startingPage "174" @default.
- W2037156739 abstract "Aims: Male breast cancer represents - mor aggressiveness and drug resistance. CSCs are characterized by CD44 and/or ALDH1 expression. In this study, we investigated their expression in male breast cancer. Method: Two in situ ductal carcinoma (DCIS) and 18 invasive duc- tal carcinoma (IDC) male breast cancer cases were studied with Jefferson IRB approval. Membrane staining of CD44 was scored by the percentage of positivity. Cytoplasmic expression of ALDH1 was considered positive. Results: Ten cases had high CD44 expression, which were all IDC. Both DCIS and in situ component of IDC were CD44 low. ALDH1 was only positive in 15 IDCs. ALDH1+ cells were mostly in the invasive component. Both DCIS cases were negative for ALDH1. Among the 15 ALDH1+ IDCs, five with only invasive component had a higher percentage (aver- age 4.4%) of positive cells compared to the other eight with in situ components (average 2.0%). Metastatic cells in sen- tinel lymph nodes had a similar expression pattern of CD44 and ALDH1 as their primary tumor. Conclusion: CD44 and ALDH1 are expressed in male breast cancers and they are overexpressed in invasive cancer compared to carcinoma in situ. These findings suggest that CSCs play an important role in the progression to invasive carcinoma." @default.
- W2037156739 created "2016-06-24" @default.
- W2037156739 creator A5021166773 @default.
- W2037156739 creator A5024095283 @default.
- W2037156739 creator A5064610744 @default.
- W2037156739 date "2013-01-01" @default.
- W2037156739 modified "2023-10-18" @default.
- W2037156739 title "Study of the Expression of ALDH1 and CD44 Stem Cell Markers in Male Breast Cancers" @default.
- W2037156739 cites W1495595158 @default.
- W2037156739 cites W1905076687 @default.
- W2037156739 cites W1966063402 @default.
- W2037156739 cites W1983158109 @default.
- W2037156739 cites W2010458398 @default.
- W2037156739 cites W2023316892 @default.
- W2037156739 cites W2029944894 @default.
- W2037156739 cites W2033389149 @default.
- W2037156739 cites W2036750803 @default.
- W2037156739 cites W2077702574 @default.
- W2037156739 cites W2078142880 @default.
- W2037156739 cites W2085134335 @default.
- W2037156739 cites W2090982381 @default.
- W2037156739 cites W2099797262 @default.
- W2037156739 cites W2102085111 @default.
- W2037156739 cites W2105916911 @default.
- W2037156739 cites W2124659104 @default.
- W2037156739 cites W2131011879 @default.
- W2037156739 cites W2143383125 @default.
- W2037156739 cites W2146962287 @default.
- W2037156739 cites W2147787153 @default.
- W2037156739 cites W2148320927 @default.
- W2037156739 cites W2151386025 @default.
- W2037156739 cites W2155390148 @default.
- W2037156739 cites W2155522744 @default.
- W2037156739 cites W2167118934 @default.
- W2037156739 cites W2261357493 @default.
- W2037156739 cites W2318106347 @default.
- W2037156739 doi "https://doi.org/10.4236/ojpathology.2013.34032" @default.
- W2037156739 hasPublicationYear "2013" @default.
- W2037156739 type Work @default.
- W2037156739 sameAs 2037156739 @default.
- W2037156739 citedByCount "0" @default.
- W2037156739 crossrefType "journal-article" @default.
- W2037156739 hasAuthorship W2037156739A5021166773 @default.
- W2037156739 hasAuthorship W2037156739A5024095283 @default.
- W2037156739 hasAuthorship W2037156739A5064610744 @default.
- W2037156739 hasBestOaLocation W20371567391 @default.
- W2037156739 hasConcept C121608353 @default.
- W2037156739 hasConcept C126322002 @default.
- W2037156739 hasConcept C142724271 @default.
- W2037156739 hasConcept C143998085 @default.
- W2037156739 hasConcept C1491633281 @default.
- W2037156739 hasConcept C204232928 @default.
- W2037156739 hasConcept C2780862961 @default.
- W2037156739 hasConcept C2780932548 @default.
- W2037156739 hasConcept C502942594 @default.
- W2037156739 hasConcept C530470458 @default.
- W2037156739 hasConcept C54355233 @default.
- W2037156739 hasConcept C55427017 @default.
- W2037156739 hasConcept C71924100 @default.
- W2037156739 hasConcept C86803240 @default.
- W2037156739 hasConceptScore W2037156739C121608353 @default.
- W2037156739 hasConceptScore W2037156739C126322002 @default.
- W2037156739 hasConceptScore W2037156739C142724271 @default.
- W2037156739 hasConceptScore W2037156739C143998085 @default.
- W2037156739 hasConceptScore W2037156739C1491633281 @default.
- W2037156739 hasConceptScore W2037156739C204232928 @default.
- W2037156739 hasConceptScore W2037156739C2780862961 @default.
- W2037156739 hasConceptScore W2037156739C2780932548 @default.
- W2037156739 hasConceptScore W2037156739C502942594 @default.
- W2037156739 hasConceptScore W2037156739C530470458 @default.
- W2037156739 hasConceptScore W2037156739C54355233 @default.
- W2037156739 hasConceptScore W2037156739C55427017 @default.
- W2037156739 hasConceptScore W2037156739C71924100 @default.
- W2037156739 hasConceptScore W2037156739C86803240 @default.
- W2037156739 hasIssue "04" @default.
- W2037156739 hasLocation W20371567391 @default.
- W2037156739 hasOpenAccess W2037156739 @default.
- W2037156739 hasPrimaryLocation W20371567391 @default.
- W2037156739 hasRelatedWork W1983201135 @default.
- W2037156739 hasRelatedWork W2034615970 @default.
- W2037156739 hasRelatedWork W2038489646 @default.
- W2037156739 hasRelatedWork W2053363358 @default.
- W2037156739 hasRelatedWork W2071015820 @default.
- W2037156739 hasRelatedWork W2136256100 @default.
- W2037156739 hasRelatedWork W2341694940 @default.
- W2037156739 hasRelatedWork W3008610168 @default.
- W2037156739 hasRelatedWork W3093180689 @default.
- W2037156739 hasRelatedWork W4226247105 @default.
- W2037156739 hasVolume "03" @default.
- W2037156739 isParatext "false" @default.
- W2037156739 isRetracted "false" @default.
- W2037156739 magId "2037156739" @default.
- W2037156739 workType "article" @default.