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- W2037157047 abstract "The development and evaluation of a vaccine against infectious laryngotracheitis virus (ILTV) using an avirulent Australian strain propagated in chicken embryo kidney cell culture is described. Yields of cell culture-grown vaccine virus per embryo were at least as high as yields obtained by the Chorio-allantoic Membrane (CAM) method. Freeze-dried preparations of stabilized cell culture vaccine showed no loss in infectivity after storage at 4°C for 12 months. In a dose-response trial using 9-day-old ILTV-susceptible chickens vaccinated by the ocular route, the 50% protective dose against challenge with virulent ILTV was shown to be approximately 100 plaque-forming units per bird." @default.
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- W2037157047 date "1979-01-01" @default.
- W2037157047 modified "2023-09-25" @default.
- W2037157047 title "The development and evaluation of a cell culture vaccine against infectious laryngotracheitis virus" @default.
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- W2037157047 doi "https://doi.org/10.1016/s0092-1157(79)80039-6" @default.
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