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- W2037170412 abstract "In this paper, we consider identifying the minimum effective dose (MED) in a dose–response study when survival data are subject to random right-censorship, where the MED is defined to be the smallest dose level under study that has survival advantage over the zero-dose control. To this end, we suggest single-step-down testing procedures based on three different types of weighted logrank statistics, respectively. The comparative results of a Monte Carlo error rate and power/bias study for a variety of survival and censoring distributions are then presented and discussed. The application of the testing procedures for identifying the MED is finally illustrated by using a numerical example of prostate cancer data." @default.
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- W2037170412 date "2007-03-01" @default.
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- W2037170412 title "Identification of the minimum effective dose for right-censored survival data" @default.
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- W2037170412 doi "https://doi.org/10.1016/j.csda.2006.11.017" @default.
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