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- W2037173657 abstract "Recently, several reports have been published about abnormal purine and pyrimidine metabolism in leukemic cells as compared to normal peripheral blood cells. Enzyme activities1,2 as well as metabolite concentrations3,4 have been studied. These studies demonstrated marked differences in the activities of many enzymes controling purine and pyrimidine metabolism in leukemic cells, such as adenosine deaminase, purine nucleoside Phosphorylase and terminal deoxynucleotidyl transferase. De Abreu et al.3 determined significantly increased concentrations of adenine and uracil nucleotides in the lymphoblasts of patients with non-B, non-T acute lymphoblastic leukemia. Liebes et al.4 found increased concentrations of nicotinamide adenine nucelotides in lymphoid cells of patients with chronic lymphatic leukemia." @default.
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- W2037173657 date "1986-01-01" @default.
- W2037173657 modified "2023-09-23" @default.
- W2037173657 title "Imbalance in Nucleotide Pools of Myeloid Leukemia Cells and HL-60 Cells: Correlation with Cell Cycle Phase, Cell Proliferation and Differentiation" @default.
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- W2037173657 doi "https://doi.org/10.1007/978-1-4684-1248-2_68" @default.
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