FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037194768> ?p ?o ?g. }

• W2037194768 endingPage "46" @default.
• W2037194768 startingPage "41" @default.
• W2037194768 abstract "Polychlorinated biphenyls, certain polychlorinated dibenzo-p-dioxins and certain polychlorinated dibenzofurans cause a variety of biological effects in experimental animals. The mechanism of the induction of certain enzymes is perhaps best understood. That is, there is binding of certain chlorinated biphenyls, dibenzo-p-dioxins and dibenzofurans to a receptor, translocation of the compound-receptor complex into the nucleus followed by an increased activity of a number of enzymes in the cell. Although the concentration of this receptor in various tissues of some mouse strains correlates well with the intensity of some of the biological effects observed in the mouse strains exposed to these compounds, this correlation apparently does not extend across various species. The current evidence suggests that the acute toxic effects of TCDD in various species is in some way associated with binding of TCDD to the receptor. However, biological effects of TCDD in addition to those resulting from binding to the receptor may be required to produce acute toxicity and, perhaps, other effects. The acute toxic effects of TCDD are probably caused by the parent compound rather than metabolites; however, this conclusion must be viewed as tentative. Also, it cannot be excluded at this time that biological effects other than acute toxicity may be caused by metabolites of TCDD. Finally, the acute toxic effects of TCDD appear not to be related, at least not directly, to the rate of metabolism of TCDD in experimental animals nor to the half-life of excretion." @default.
• W2037194768 created "2016-06-24" @default.
• W2037194768 creator A5033593546 @default.
• W2037194768 date "1985-05-01" @default.
• W2037194768 modified "2023-09-29" @default.
• W2037194768 title "Mechanisms of the biological effects of PCBs, polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in experimental animals." @default.
• W2037194768 cites W1577296862 @default.
• W2037194768 cites W1591874105 @default.
• W2037194768 cites W1875294959 @default.
• W2037194768 cites W1963665444 @default.
• W2037194768 cites W1971283548 @default.
• W2037194768 cites W1979870899 @default.
• W2037194768 cites W1990789063 @default.
• W2037194768 cites W1993224368 @default.
• W2037194768 cites W1996970676 @default.
• W2037194768 cites W1999989358 @default.
• W2037194768 cites W2008143869 @default.
• W2037194768 cites W2023960674 @default.
• W2037194768 cites W2028229334 @default.
• W2037194768 cites W2029770762 @default.
• W2037194768 cites W2040010445 @default.
• W2037194768 cites W2042049062 @default.
• W2037194768 cites W2048640056 @default.
• W2037194768 cites W2055064469 @default.
• W2037194768 cites W2061427284 @default.
• W2037194768 cites W2065015994 @default.
• W2037194768 cites W2070674364 @default.
• W2037194768 cites W2074843250 @default.
• W2037194768 cites W2076486040 @default.
• W2037194768 cites W2084142664 @default.
• W2037194768 cites W2088477195 @default.
• W2037194768 cites W2090997695 @default.
• W2037194768 cites W2095384906 @default.
• W2037194768 cites W2162067613 @default.
• W2037194768 cites W2162919180 @default.
• W2037194768 cites W2259916068 @default.
• W2037194768 cites W2293100977 @default.
• W2037194768 cites W2397927814 @default.
• W2037194768 cites W2467514910 @default.
• W2037194768 doi "https://doi.org/10.1289/ehp.856041" @default.
• W2037194768 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1568561" @default.
• W2037194768 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2992926" @default.
• W2037194768 hasPublicationYear "1985" @default.
• W2037194768 type Work @default.
• W2037194768 sameAs 2037194768 @default.
• W2037194768 citedByCount "19" @default.
• W2037194768 countsByYear W20371947682014 @default.
• W2037194768 countsByYear W20371947682017 @default.
• W2037194768 crossrefType "journal-article" @default.
• W2037194768 hasAuthorship W2037194768A5033593546 @default.
• W2037194768 hasBestOaLocation W20371947681 @default.
• W2037194768 hasConcept C104317684 @default.
• W2037194768 hasConcept C107872376 @default.
• W2037194768 hasConcept C114246631 @default.
• W2037194768 hasConcept C116073593 @default.
• W2037194768 hasConcept C116263406 @default.
• W2037194768 hasConcept C150194340 @default.
• W2037194768 hasConcept C170493617 @default.
• W2037194768 hasConcept C178790620 @default.
• W2037194768 hasConcept C181199279 @default.
• W2037194768 hasConcept C185592680 @default.
• W2037194768 hasConcept C202751555 @default.
• W2037194768 hasConcept C2777236388 @default.
• W2037194768 hasConcept C29730261 @default.
• W2037194768 hasConcept C55493867 @default.
• W2037194768 hasConcept C62231903 @default.
• W2037194768 hasConcept C86803240 @default.
• W2037194768 hasConcept C98274493 @default.
• W2037194768 hasConcept C9927688 @default.
• W2037194768 hasConceptScore W2037194768C104317684 @default.
• W2037194768 hasConceptScore W2037194768C107872376 @default.
• W2037194768 hasConceptScore W2037194768C114246631 @default.
• W2037194768 hasConceptScore W2037194768C116073593 @default.
• W2037194768 hasConceptScore W2037194768C116263406 @default.
• W2037194768 hasConceptScore W2037194768C150194340 @default.
• W2037194768 hasConceptScore W2037194768C170493617 @default.
• W2037194768 hasConceptScore W2037194768C178790620 @default.
• W2037194768 hasConceptScore W2037194768C181199279 @default.
• W2037194768 hasConceptScore W2037194768C185592680 @default.
• W2037194768 hasConceptScore W2037194768C202751555 @default.
• W2037194768 hasConceptScore W2037194768C2777236388 @default.
• W2037194768 hasConceptScore W2037194768C29730261 @default.
• W2037194768 hasConceptScore W2037194768C55493867 @default.
• W2037194768 hasConceptScore W2037194768C62231903 @default.
• W2037194768 hasConceptScore W2037194768C86803240 @default.
• W2037194768 hasConceptScore W2037194768C98274493 @default.
• W2037194768 hasConceptScore W2037194768C9927688 @default.
• W2037194768 hasLocation W20371947681 @default.
• W2037194768 hasLocation W20371947682 @default.
• W2037194768 hasLocation W20371947683 @default.
• W2037194768 hasLocation W20371947684 @default.
• W2037194768 hasOpenAccess W2037194768 @default.
• W2037194768 hasPrimaryLocation W20371947681 @default.
• W2037194768 hasRelatedWork W1795158602 @default.
• W2037194768 hasRelatedWork W2014509727 @default.
• W2037194768 hasRelatedWork W2022114498 @default.
• W2037194768 hasRelatedWork W2037194768 @default.
• W2037194768 hasRelatedWork W2057589855 @default.

• next