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- W2037199982 abstract "To discuss the current understanding of the pathogenesis, natural history, and diagnosis of cardiac allograft vasculopathy, and to outline new preventive and treatment strategies.The central event in the development of allograft vasculopathy is the inflammatory response to immune or nonimmune-mediated endothelial damage. This response is characterized by the release of inflammatory cytokines, upregulation of cell-surface adhesion molecules, and the subsequent binding of leukocytes. Once induced, vascular smooth muscle cells proliferate and migrate from the media to form a neointima. Circulating progenitor cells are recruited to sites of arterial injury where they may then differentiate into smooth muscle cells. Because of its diffuse nature, allograft vasculopathy is best detected by intravascular ultrasound. Noninvasive tests, such as dobutamine echocardiography, are gaining in favor. Although the only definitive treatment is retransplantation, the immunosuppressant rapamycin can limit disease progression. Its synthetic derivative, everolimus, effectively prevented intimal hyperplasia in de novo transplant recipients.These advances have provided hope that allograft vasculopathy may finally be manageable." @default.
- W2037199982 created "2016-06-24" @default.
- W2037199982 creator A5013091913 @default.
- W2037199982 creator A5050008295 @default.
- W2037199982 date "2004-03-01" @default.
- W2037199982 modified "2023-09-30" @default.
- W2037199982 title "Cardiac allograft vasculopathy: advances in understanding its pathophysiology, prevention, and treatment" @default.
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- W2037199982 cites W1970003185 @default.
- W2037199982 cites W1973052808 @default.
- W2037199982 cites W1976989874 @default.
- W2037199982 cites W2001302467 @default.
- W2037199982 cites W2002269053 @default.
- W2037199982 cites W2003165146 @default.
- W2037199982 cites W2007105330 @default.
- W2037199982 cites W2010955416 @default.
- W2037199982 cites W2017333569 @default.
- W2037199982 cites W2019989442 @default.
- W2037199982 cites W2028542135 @default.
- W2037199982 cites W2031687741 @default.
- W2037199982 cites W2032467639 @default.
- W2037199982 cites W2035683317 @default.
- W2037199982 cites W2041389089 @default.
- W2037199982 cites W2041977741 @default.
- W2037199982 cites W2042525400 @default.
- W2037199982 cites W2042707982 @default.
- W2037199982 cites W2046293384 @default.
- W2037199982 cites W2055521003 @default.
- W2037199982 cites W2059600453 @default.
- W2037199982 cites W2062661553 @default.
- W2037199982 cites W2064044928 @default.
- W2037199982 cites W2064971849 @default.
- W2037199982 cites W2070108843 @default.
- W2037199982 cites W2075303797 @default.
- W2037199982 cites W2082148510 @default.
- W2037199982 cites W2087691980 @default.
- W2037199982 cites W2089590598 @default.
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- W2037199982 doi "https://doi.org/10.1097/00001573-200403000-00019" @default.
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