Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037209097> ?p ?o ?g. }
- W2037209097 abstract "Barbiturate actions on excitatory synaptic responses in CA 1 and dentate regions of hippocampal slices were studied to determine whether different effects occur on anatomically distinct synaptic pathways. Pentobarbital facilitated transmission between stratum radiatum inputs and CA 1 neurons at low concentrations (0.02–0.08 mM) and produced postsynaptic depression at higher concentrations. Only depression was observed for stratum oriens inputs to CA 1 and perforant path inputs to dentate granulae neurons. The (+) isomer of pentobarbital was approximately four times more potent than the (−) isomer of racemic mixture. Phenobarbital (0.04–0.12 mM) produced only depression of synaptic responses in CA 1 and dentate pathways. Comparison of effect on field excitatory postsynaptic potentials and population spike responses indicated that the barbiturates act at selective and pathway-specific sites. The results provide further evidence for specific cellular and membrane recognition sites for barbiturate action." @default.
- W2037209097 created "2016-06-24" @default.
- W2037209097 creator A5007694516 @default.
- W2037209097 creator A5088639131 @default.
- W2037209097 date "1987-03-01" @default.
- W2037209097 modified "2023-09-24" @default.
- W2037209097 title "Barbiturate effects on hippocampal excitatory synaptic responses are selective and pathway specific" @default.
- W2037209097 cites W1550302433 @default.
- W2037209097 cites W1632009755 @default.
- W2037209097 cites W1968860350 @default.
- W2037209097 cites W1971283034 @default.
- W2037209097 cites W1974914532 @default.
- W2037209097 cites W1978415367 @default.
- W2037209097 cites W1978702599 @default.
- W2037209097 cites W1990326404 @default.
- W2037209097 cites W1991506281 @default.
- W2037209097 cites W1994969247 @default.
- W2037209097 cites W1995532860 @default.
- W2037209097 cites W1996434213 @default.
- W2037209097 cites W1997315349 @default.
- W2037209097 cites W2009782005 @default.
- W2037209097 cites W2034080924 @default.
- W2037209097 cites W2049706117 @default.
- W2037209097 cites W2062730470 @default.
- W2037209097 cites W2078963381 @default.
- W2037209097 cites W2083080932 @default.
- W2037209097 cites W2083522311 @default.
- W2037209097 cites W2084898236 @default.
- W2037209097 cites W2089553401 @default.
- W2037209097 cites W2162305148 @default.
- W2037209097 cites W2411932594 @default.
- W2037209097 cites W2486348950 @default.
- W2037209097 cites W2501904478 @default.
- W2037209097 cites W87174765 @default.
- W2037209097 cites W89187360 @default.
- W2037209097 doi "https://doi.org/10.1139/y87-065" @default.
- W2037209097 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3034390" @default.
- W2037209097 hasPublicationYear "1987" @default.
- W2037209097 type Work @default.
- W2037209097 sameAs 2037209097 @default.
- W2037209097 citedByCount "24" @default.
- W2037209097 countsByYear W20372090972013 @default.
- W2037209097 countsByYear W20372090972015 @default.
- W2037209097 crossrefType "journal-article" @default.
- W2037209097 hasAuthorship W2037209097A5007694516 @default.
- W2037209097 hasAuthorship W2037209097A5088639131 @default.
- W2037209097 hasConcept C112592302 @default.
- W2037209097 hasConcept C148762608 @default.
- W2037209097 hasConcept C169760540 @default.
- W2037209097 hasConcept C170493617 @default.
- W2037209097 hasConcept C17077164 @default.
- W2037209097 hasConcept C179053475 @default.
- W2037209097 hasConcept C185592680 @default.
- W2037209097 hasConcept C197341189 @default.
- W2037209097 hasConcept C200170125 @default.
- W2037209097 hasConcept C2776168963 @default.
- W2037209097 hasConcept C2776755955 @default.
- W2037209097 hasConcept C2779277159 @default.
- W2037209097 hasConcept C2780077838 @default.
- W2037209097 hasConcept C2908647359 @default.
- W2037209097 hasConcept C55493867 @default.
- W2037209097 hasConcept C71924100 @default.
- W2037209097 hasConcept C86803240 @default.
- W2037209097 hasConcept C98274493 @default.
- W2037209097 hasConcept C99454951 @default.
- W2037209097 hasConceptScore W2037209097C112592302 @default.
- W2037209097 hasConceptScore W2037209097C148762608 @default.
- W2037209097 hasConceptScore W2037209097C169760540 @default.
- W2037209097 hasConceptScore W2037209097C170493617 @default.
- W2037209097 hasConceptScore W2037209097C17077164 @default.
- W2037209097 hasConceptScore W2037209097C179053475 @default.
- W2037209097 hasConceptScore W2037209097C185592680 @default.
- W2037209097 hasConceptScore W2037209097C197341189 @default.
- W2037209097 hasConceptScore W2037209097C200170125 @default.
- W2037209097 hasConceptScore W2037209097C2776168963 @default.
- W2037209097 hasConceptScore W2037209097C2776755955 @default.
- W2037209097 hasConceptScore W2037209097C2779277159 @default.
- W2037209097 hasConceptScore W2037209097C2780077838 @default.
- W2037209097 hasConceptScore W2037209097C2908647359 @default.
- W2037209097 hasConceptScore W2037209097C55493867 @default.
- W2037209097 hasConceptScore W2037209097C71924100 @default.
- W2037209097 hasConceptScore W2037209097C86803240 @default.
- W2037209097 hasConceptScore W2037209097C98274493 @default.
- W2037209097 hasConceptScore W2037209097C99454951 @default.
- W2037209097 hasLocation W20372090971 @default.
- W2037209097 hasLocation W20372090972 @default.
- W2037209097 hasOpenAccess W2037209097 @default.
- W2037209097 hasPrimaryLocation W20372090971 @default.
- W2037209097 hasRelatedWork W1643544035 @default.
- W2037209097 hasRelatedWork W1973163966 @default.
- W2037209097 hasRelatedWork W2033884811 @default.
- W2037209097 hasRelatedWork W2037209097 @default.
- W2037209097 hasRelatedWork W2050659941 @default.
- W2037209097 hasRelatedWork W2063566561 @default.
- W2037209097 hasRelatedWork W2083267691 @default.
- W2037209097 hasRelatedWork W2141954297 @default.
- W2037209097 hasRelatedWork W2202139434 @default.
- W2037209097 hasRelatedWork W2752743978 @default.
- W2037209097 isParatext "false" @default.
- W2037209097 isRetracted "false" @default.