Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037221631> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2037221631 endingPage "69" @default.
- W2037221631 startingPage "57" @default.
- W2037221631 abstract "The effects of 6-hydroxydopamine on the catecholamine content of the hypothalamus and other tissues, the morphology of the median eminence of the hypothalamus, and plasma corticosterone were studied after intraperitoneal injection of the drug. The effect of injecting 6-hydroxydopamine into the third ventricle of the brain in unanesthetized animals was also studied. One day after injection by either route, hypothalamic norepinephrine was reduced and plasma corticosterone was elevated, suggesting increased secretion of ACTH from the pituitary. There were degenerative changes in a small number of neurons ending in the external layer of the median eminence, while other neurons in the median eminence were unaffected. Fifteen days after injection, hypothalamic norepinephrine and plasma corticosterone had returned to normal in the animals given 6-hydroxydopamine intraperitoneally. In the rats injected intraventricularly, hypothalamic norepinephrine was still reduced but plasma corticosterone was normal. In both groups at 15 days, neuronal debris had accumulated in phagocytic cells, but most neurons appeared normal. The data provide evidence that norepinephrine-containing neurons end in the external layer of the median eminence. They are also consistent with the hypothesis that a central adrenergic system inhibits ACTH secretion. Fifteen days after injection, an as yet unknown mechanism compensates for the decrease in norepinephrine content and ACTH secretion returns to normal." @default.
- W2037221631 created "2016-06-24" @default.
- W2037221631 creator A5026643936 @default.
- W2037221631 creator A5033125462 @default.
- W2037221631 creator A5083164413 @default.
- W2037221631 date "1974-09-01" @default.
- W2037221631 modified "2023-09-23" @default.
- W2037221631 title "Effect of 6-hydroxydopamine on hypothalamic norepinephrine and dopamine content, ultrastructure of the median eminence, and plasma corticosterone" @default.
- W2037221631 cites W1970001287 @default.
- W2037221631 cites W1997339078 @default.
- W2037221631 cites W1998474711 @default.
- W2037221631 cites W2019126938 @default.
- W2037221631 cites W2026921888 @default.
- W2037221631 cites W2038690648 @default.
- W2037221631 cites W2050709677 @default.
- W2037221631 cites W2086450872 @default.
- W2037221631 cites W2088133721 @default.
- W2037221631 cites W2092452199 @default.
- W2037221631 doi "https://doi.org/10.1016/0006-8993(74)90353-9" @default.
- W2037221631 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4376442" @default.
- W2037221631 hasPublicationYear "1974" @default.
- W2037221631 type Work @default.
- W2037221631 sameAs 2037221631 @default.
- W2037221631 citedByCount "59" @default.
- W2037221631 countsByYear W20372216312022 @default.
- W2037221631 crossrefType "journal-article" @default.
- W2037221631 hasAuthorship W2037221631A5026643936 @default.
- W2037221631 hasAuthorship W2037221631A5033125462 @default.
- W2037221631 hasAuthorship W2037221631A5083164413 @default.
- W2037221631 hasConcept C126322002 @default.
- W2037221631 hasConcept C134018914 @default.
- W2037221631 hasConcept C137183658 @default.
- W2037221631 hasConcept C170493617 @default.
- W2037221631 hasConcept C185592680 @default.
- W2037221631 hasConcept C187714386 @default.
- W2037221631 hasConcept C2775864247 @default.
- W2037221631 hasConcept C2775894120 @default.
- W2037221631 hasConcept C2777003273 @default.
- W2037221631 hasConcept C2778514916 @default.
- W2037221631 hasConcept C2779067335 @default.
- W2037221631 hasConcept C2780352252 @default.
- W2037221631 hasConcept C2911016594 @default.
- W2037221631 hasConcept C513476851 @default.
- W2037221631 hasConcept C71315377 @default.
- W2037221631 hasConcept C71924100 @default.
- W2037221631 hasConcept C86803240 @default.
- W2037221631 hasConceptScore W2037221631C126322002 @default.
- W2037221631 hasConceptScore W2037221631C134018914 @default.
- W2037221631 hasConceptScore W2037221631C137183658 @default.
- W2037221631 hasConceptScore W2037221631C170493617 @default.
- W2037221631 hasConceptScore W2037221631C185592680 @default.
- W2037221631 hasConceptScore W2037221631C187714386 @default.
- W2037221631 hasConceptScore W2037221631C2775864247 @default.
- W2037221631 hasConceptScore W2037221631C2775894120 @default.
- W2037221631 hasConceptScore W2037221631C2777003273 @default.
- W2037221631 hasConceptScore W2037221631C2778514916 @default.
- W2037221631 hasConceptScore W2037221631C2779067335 @default.
- W2037221631 hasConceptScore W2037221631C2780352252 @default.
- W2037221631 hasConceptScore W2037221631C2911016594 @default.
- W2037221631 hasConceptScore W2037221631C513476851 @default.
- W2037221631 hasConceptScore W2037221631C71315377 @default.
- W2037221631 hasConceptScore W2037221631C71924100 @default.
- W2037221631 hasConceptScore W2037221631C86803240 @default.
- W2037221631 hasIssue "1" @default.
- W2037221631 hasLocation W20372216311 @default.
- W2037221631 hasLocation W20372216312 @default.
- W2037221631 hasOpenAccess W2037221631 @default.
- W2037221631 hasPrimaryLocation W20372216311 @default.
- W2037221631 hasRelatedWork W1966437072 @default.
- W2037221631 hasRelatedWork W1978175539 @default.
- W2037221631 hasRelatedWork W1997653766 @default.
- W2037221631 hasRelatedWork W2011727899 @default.
- W2037221631 hasRelatedWork W2032496869 @default.
- W2037221631 hasRelatedWork W2036485448 @default.
- W2037221631 hasRelatedWork W2037221631 @default.
- W2037221631 hasRelatedWork W2084435836 @default.
- W2037221631 hasRelatedWork W2094511447 @default.
- W2037221631 hasRelatedWork W2147413277 @default.
- W2037221631 hasVolume "78" @default.
- W2037221631 isParatext "false" @default.
- W2037221631 isRetracted "false" @default.
- W2037221631 magId "2037221631" @default.
- W2037221631 workType "article" @default.