Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037221825> ?p ?o ?g. }
- W2037221825 endingPage "787" @default.
- W2037221825 startingPage "779" @default.
- W2037221825 abstract "We have carried out experiments designed to ask if it is possible to convert a secretory protein into an integral membrane protein by appending the membrane spanning domain of an integral membrane protein to its carboxy terminus. We first obtained expression of a cDNA clone encoding rat growth hormone (rGH) in eucaryotic cells, and found that this protein was secreted. We then constructed and expressed a hybrid gene encoding rGH fused to the membrane spanning and cytoplasmic domains of the vesicular stomatitis virus (VSV) glycoprotein (G). This fusion protein was anchored in microsomal membranes in the expected transmembrane configuration. The fusion protein was transported to the Golgi apparatus, and was esterified to palmitic acid, but it was not transported to the cell surface. We suggest that the sorting signal which allows rapid secretion of soluble rGH does not function when the protein is bound to the membrane." @default.
- W2037221825 created "2016-06-24" @default.
- W2037221825 creator A5030957947 @default.
- W2037221825 creator A5081249676 @default.
- W2037221825 date "1984-07-01" @default.
- W2037221825 modified "2023-10-17" @default.
- W2037221825 title "Conversion of a secretory protein into a transmembrane protein results in its transport to the golgi complex but not to the cell surface" @default.
- W2037221825 cites W1508770301 @default.
- W2037221825 cites W1603798629 @default.
- W2037221825 cites W1665121191 @default.
- W2037221825 cites W1731705023 @default.
- W2037221825 cites W1876513378 @default.
- W2037221825 cites W1878494724 @default.
- W2037221825 cites W1884088573 @default.
- W2037221825 cites W1983926699 @default.
- W2037221825 cites W1984513339 @default.
- W2037221825 cites W1990315003 @default.
- W2037221825 cites W1993794808 @default.
- W2037221825 cites W1995476615 @default.
- W2037221825 cites W2009580887 @default.
- W2037221825 cites W2016417523 @default.
- W2037221825 cites W2017284486 @default.
- W2037221825 cites W2023125347 @default.
- W2037221825 cites W2027407556 @default.
- W2037221825 cites W2059974282 @default.
- W2037221825 cites W2063115478 @default.
- W2037221825 cites W2063272862 @default.
- W2037221825 cites W2067093784 @default.
- W2037221825 cites W2071013566 @default.
- W2037221825 cites W2080185465 @default.
- W2037221825 cites W2085062936 @default.
- W2037221825 cites W2088167128 @default.
- W2037221825 cites W2089015567 @default.
- W2037221825 cites W2097111479 @default.
- W2037221825 cites W2130452852 @default.
- W2037221825 cites W276869058 @default.
- W2037221825 doi "https://doi.org/10.1016/0092-8674(84)90413-6" @default.
- W2037221825 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6589049" @default.
- W2037221825 hasPublicationYear "1984" @default.
- W2037221825 type Work @default.
- W2037221825 sameAs 2037221825 @default.
- W2037221825 citedByCount "119" @default.
- W2037221825 countsByYear W20372218252015 @default.
- W2037221825 countsByYear W20372218252018 @default.
- W2037221825 crossrefType "journal-article" @default.
- W2037221825 hasAuthorship W2037221825A5030957947 @default.
- W2037221825 hasAuthorship W2037221825A5081249676 @default.
- W2037221825 hasConcept C104317684 @default.
- W2037221825 hasConcept C108625454 @default.
- W2037221825 hasConcept C118892022 @default.
- W2037221825 hasConcept C119062480 @default.
- W2037221825 hasConcept C123894998 @default.
- W2037221825 hasConcept C144647389 @default.
- W2037221825 hasConcept C146033667 @default.
- W2037221825 hasConcept C156399914 @default.
- W2037221825 hasConcept C158617107 @default.
- W2037221825 hasConcept C161200384 @default.
- W2037221825 hasConcept C170493617 @default.
- W2037221825 hasConcept C180196505 @default.
- W2037221825 hasConcept C24530287 @default.
- W2037221825 hasConcept C2777459641 @default.
- W2037221825 hasConcept C2779057330 @default.
- W2037221825 hasConcept C40767141 @default.
- W2037221825 hasConcept C41625074 @default.
- W2037221825 hasConcept C49039625 @default.
- W2037221825 hasConcept C52789158 @default.
- W2037221825 hasConcept C54355233 @default.
- W2037221825 hasConcept C55493867 @default.
- W2037221825 hasConcept C560191 @default.
- W2037221825 hasConcept C57581600 @default.
- W2037221825 hasConcept C6492254 @default.
- W2037221825 hasConcept C81885089 @default.
- W2037221825 hasConcept C86803240 @default.
- W2037221825 hasConcept C95444343 @default.
- W2037221825 hasConceptScore W2037221825C104317684 @default.
- W2037221825 hasConceptScore W2037221825C108625454 @default.
- W2037221825 hasConceptScore W2037221825C118892022 @default.
- W2037221825 hasConceptScore W2037221825C119062480 @default.
- W2037221825 hasConceptScore W2037221825C123894998 @default.
- W2037221825 hasConceptScore W2037221825C144647389 @default.
- W2037221825 hasConceptScore W2037221825C146033667 @default.
- W2037221825 hasConceptScore W2037221825C156399914 @default.
- W2037221825 hasConceptScore W2037221825C158617107 @default.
- W2037221825 hasConceptScore W2037221825C161200384 @default.
- W2037221825 hasConceptScore W2037221825C170493617 @default.
- W2037221825 hasConceptScore W2037221825C180196505 @default.
- W2037221825 hasConceptScore W2037221825C24530287 @default.
- W2037221825 hasConceptScore W2037221825C2777459641 @default.
- W2037221825 hasConceptScore W2037221825C2779057330 @default.
- W2037221825 hasConceptScore W2037221825C40767141 @default.
- W2037221825 hasConceptScore W2037221825C41625074 @default.
- W2037221825 hasConceptScore W2037221825C49039625 @default.
- W2037221825 hasConceptScore W2037221825C52789158 @default.
- W2037221825 hasConceptScore W2037221825C54355233 @default.
- W2037221825 hasConceptScore W2037221825C55493867 @default.
- W2037221825 hasConceptScore W2037221825C560191 @default.
- W2037221825 hasConceptScore W2037221825C57581600 @default.
- W2037221825 hasConceptScore W2037221825C6492254 @default.