FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037222483> ?p ?o ?g. }

• W2037222483 endingPage "254" @default.
• W2037222483 startingPage "245" @default.
• W2037222483 abstract "Regulatory T cells (Tregs) are a specific subset of T lymphocytes that regulate the function of other subsets of lymphocytes. Contradictory results have been reported regarding the role of Tregs in lung fibrosis. We wished to clarify the role of Tregs in the early and late stages of bleomycin-induced lung fibrosis in mice by depleting them with anti-CD25+ antibody (PC61). Mice treated with PC61 in early stages had significantly decreased number of CD4+CD25+ T cells compared to mice treated with the isotype control. The number of inflammatory cells, the concentrations of collagen, TGFβ1, the content of collagen and hydroxyproline in lung tissue were significantly reduced in PC61-treated mice compared to mice treated with the isotype control group. Pathological examination of the lung also disclosed reduced fibrotic changes and decreased fibrosis score in the PC61 group compared to control group. By contrast, mice treated with PC61 in late stages of the disease showed more infiltration of inflammatory cells and higher fibrotic score and hydroxyproline content in the lungs than mice treated with the isotype control. Our results suggest that Tregs play a detrimental role in early stages but protective role in late stages of pulmonary fibrosis in mice." @default.
• W2037222483 created "2016-06-24" @default.
• W2037222483 creator A5001536990 @default.
• W2037222483 creator A5002918726 @default.
• W2037222483 creator A5014879220 @default.
• W2037222483 creator A5017823668 @default.
• W2037222483 creator A5018985536 @default.
• W2037222483 creator A5025223590 @default.
• W2037222483 creator A5033672486 @default.
• W2037222483 creator A5039133602 @default.
• W2037222483 creator A5051760258 @default.
• W2037222483 creator A5052057338 @default.
• W2037222483 creator A5055923444 @default.
• W2037222483 creator A5062744464 @default.
• W2037222483 creator A5064879694 @default.
• W2037222483 creator A5075886569 @default.
• W2037222483 creator A5081913129 @default.
• W2037222483 date "2013-02-01" @default.
• W2037222483 modified "2023-10-14" @default.
• W2037222483 title "Differential role of regulatory T cells in early and late stages of pulmonary fibrosis" @default.
• W2037222483 cites W1483540731 @default.
• W2037222483 cites W1595770568 @default.
• W2037222483 cites W1976574577 @default.
• W2037222483 cites W1980325398 @default.
• W2037222483 cites W1983197863 @default.
• W2037222483 cites W1992905570 @default.
• W2037222483 cites W1993311951 @default.
• W2037222483 cites W1993559550 @default.
• W2037222483 cites W2003786327 @default.
• W2037222483 cites W2004697839 @default.
• W2037222483 cites W2025083720 @default.
• W2037222483 cites W2027264123 @default.
• W2037222483 cites W2038838786 @default.
• W2037222483 cites W2055835653 @default.
• W2037222483 cites W2056566791 @default.
• W2037222483 cites W2064307892 @default.
• W2037222483 cites W2075400164 @default.
• W2037222483 cites W2075876102 @default.
• W2037222483 cites W2093312070 @default.
• W2037222483 cites W2096257246 @default.
• W2037222483 cites W2111139868 @default.
• W2037222483 cites W2114330584 @default.
• W2037222483 cites W2124912046 @default.
• W2037222483 cites W2125241840 @default.
• W2037222483 cites W2134560060 @default.
• W2037222483 cites W2143801222 @default.
• W2037222483 cites W2146938802 @default.
• W2037222483 cites W2162149101 @default.
• W2037222483 cites W2164998164 @default.
• W2037222483 cites W2167211373 @default.
• W2037222483 cites W2167351713 @default.
• W2037222483 doi "https://doi.org/10.1016/j.imbio.2012.05.020" @default.
• W2037222483 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22739236" @default.
• W2037222483 hasPublicationYear "2013" @default.
• W2037222483 type Work @default.
• W2037222483 sameAs 2037222483 @default.
• W2037222483 citedByCount "66" @default.
• W2037222483 countsByYear W20372224832012 @default.
• W2037222483 countsByYear W20372224832013 @default.
• W2037222483 countsByYear W20372224832014 @default.
• W2037222483 countsByYear W20372224832015 @default.
• W2037222483 countsByYear W20372224832016 @default.
• W2037222483 countsByYear W20372224832017 @default.
• W2037222483 countsByYear W20372224832018 @default.
• W2037222483 countsByYear W20372224832019 @default.
• W2037222483 countsByYear W20372224832020 @default.
• W2037222483 countsByYear W20372224832021 @default.
• W2037222483 countsByYear W20372224832022 @default.
• W2037222483 countsByYear W20372224832023 @default.
• W2037222483 crossrefType "journal-article" @default.
• W2037222483 hasAuthorship W2037222483A5001536990 @default.
• W2037222483 hasAuthorship W2037222483A5002918726 @default.
• W2037222483 hasAuthorship W2037222483A5014879220 @default.
• W2037222483 hasAuthorship W2037222483A5017823668 @default.
• W2037222483 hasAuthorship W2037222483A5018985536 @default.
• W2037222483 hasAuthorship W2037222483A5025223590 @default.
• W2037222483 hasAuthorship W2037222483A5033672486 @default.
• W2037222483 hasAuthorship W2037222483A5039133602 @default.
• W2037222483 hasAuthorship W2037222483A5051760258 @default.
• W2037222483 hasAuthorship W2037222483A5052057338 @default.
• W2037222483 hasAuthorship W2037222483A5055923444 @default.
• W2037222483 hasAuthorship W2037222483A5062744464 @default.
• W2037222483 hasAuthorship W2037222483A5064879694 @default.
• W2037222483 hasAuthorship W2037222483A5075886569 @default.
• W2037222483 hasAuthorship W2037222483A5081913129 @default.
• W2037222483 hasConcept C126322002 @default.
• W2037222483 hasConcept C134018914 @default.
• W2037222483 hasConcept C142724271 @default.
• W2037222483 hasConcept C159654299 @default.
• W2037222483 hasConcept C203014093 @default.
• W2037222483 hasConcept C207886595 @default.
• W2037222483 hasConcept C2776090121 @default.
• W2037222483 hasConcept C2776232574 @default.
• W2037222483 hasConcept C2776694085 @default.
• W2037222483 hasConcept C2777714996 @default.
• W2037222483 hasConcept C2777991845 @default.
• W2037222483 hasConcept C2778296632 @default.
• W2037222483 hasConcept C2779797417 @default.

• next