Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037223075> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2037223075 endingPage "306" @default.
- W2037223075 startingPage "303" @default.
- W2037223075 abstract "The lack of a convenient diagnostic method for onchocerciasis has motivated attempts to develop better detection techniques. Preliminary results indicate that a dot blot assay of the total immunoglobulin G (IgG) response to an easily available and simply prepared Tris buffer soluble fraction (TSF) of whole female worms may be applicable in the field as a first screening method. The specificity of the assay is improved by using a partially purified fraction of TSF of which the dominant component is a 23 kDa protein antigen, PakF. The IgG response to PakF was 100% sensitive and at least as specific as the IgG4 response to TSF. Sera from 189 individuals including onchocerciasis patients and apparently uninfected control subjects from an endemic area and from an urban area in Ghana were screened. The specificity of the assay with urban and endemic control sera was 93% and 68% respectively. The dot blot assay has advantages over the existing skin snip and enzyme-linked immunosorbent assay techniques in terms of simplicity, cost, consumption of antigen, risk of spreading other infections, and patient comfort." @default.
- W2037223075 created "2016-06-24" @default.
- W2037223075 creator A5023540486 @default.
- W2037223075 creator A5038725411 @default.
- W2037223075 creator A5047942565 @default.
- W2037223075 creator A5050616249 @default.
- W2037223075 creator A5053367576 @default.
- W2037223075 creator A5075919129 @default.
- W2037223075 creator A5082220443 @default.
- W2037223075 creator A5085848261 @default.
- W2037223075 date "1994-05-01" @default.
- W2037223075 modified "2023-10-16" @default.
- W2037223075 title "A simple dot blot assay adaptable for field use in the diagnosis of onchocerciasis: preparation of an adult worm antigen fraction which enhances sensitivity and specificity" @default.
- W2037223075 cites W1781996617 @default.
- W2037223075 cites W1980979749 @default.
- W2037223075 cites W1982137939 @default.
- W2037223075 cites W2010153736 @default.
- W2037223075 cites W2038449026 @default.
- W2037223075 cites W2117004758 @default.
- W2037223075 cites W2410694950 @default.
- W2037223075 cites W2440391485 @default.
- W2037223075 cites W2467501021 @default.
- W2037223075 cites W2955710918 @default.
- W2037223075 cites W4293247451 @default.
- W2037223075 doi "https://doi.org/10.1016/0035-9203(94)90090-6" @default.
- W2037223075 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7974670" @default.
- W2037223075 hasPublicationYear "1994" @default.
- W2037223075 type Work @default.
- W2037223075 sameAs 2037223075 @default.
- W2037223075 citedByCount "17" @default.
- W2037223075 countsByYear W20372230752014 @default.
- W2037223075 countsByYear W20372230752015 @default.
- W2037223075 countsByYear W20372230752016 @default.
- W2037223075 countsByYear W20372230752017 @default.
- W2037223075 countsByYear W20372230752018 @default.
- W2037223075 countsByYear W20372230752019 @default.
- W2037223075 countsByYear W20372230752021 @default.
- W2037223075 countsByYear W20372230752022 @default.
- W2037223075 crossrefType "journal-article" @default.
- W2037223075 hasAuthorship W2037223075A5023540486 @default.
- W2037223075 hasAuthorship W2037223075A5038725411 @default.
- W2037223075 hasAuthorship W2037223075A5047942565 @default.
- W2037223075 hasAuthorship W2037223075A5050616249 @default.
- W2037223075 hasAuthorship W2037223075A5053367576 @default.
- W2037223075 hasAuthorship W2037223075A5075919129 @default.
- W2037223075 hasAuthorship W2037223075A5082220443 @default.
- W2037223075 hasAuthorship W2037223075A5085848261 @default.
- W2037223075 hasConcept C104317684 @default.
- W2037223075 hasConcept C130840561 @default.
- W2037223075 hasConcept C147483822 @default.
- W2037223075 hasConcept C153911025 @default.
- W2037223075 hasConcept C159654299 @default.
- W2037223075 hasConcept C203014093 @default.
- W2037223075 hasConcept C2776415932 @default.
- W2037223075 hasConcept C2780727990 @default.
- W2037223075 hasConcept C552990157 @default.
- W2037223075 hasConcept C55493867 @default.
- W2037223075 hasConcept C86803240 @default.
- W2037223075 hasConceptScore W2037223075C104317684 @default.
- W2037223075 hasConceptScore W2037223075C130840561 @default.
- W2037223075 hasConceptScore W2037223075C147483822 @default.
- W2037223075 hasConceptScore W2037223075C153911025 @default.
- W2037223075 hasConceptScore W2037223075C159654299 @default.
- W2037223075 hasConceptScore W2037223075C203014093 @default.
- W2037223075 hasConceptScore W2037223075C2776415932 @default.
- W2037223075 hasConceptScore W2037223075C2780727990 @default.
- W2037223075 hasConceptScore W2037223075C552990157 @default.
- W2037223075 hasConceptScore W2037223075C55493867 @default.
- W2037223075 hasConceptScore W2037223075C86803240 @default.
- W2037223075 hasIssue "3" @default.
- W2037223075 hasLocation W20372230751 @default.
- W2037223075 hasLocation W20372230752 @default.
- W2037223075 hasOpenAccess W2037223075 @default.
- W2037223075 hasPrimaryLocation W20372230751 @default.
- W2037223075 hasRelatedWork W2004225754 @default.
- W2037223075 hasRelatedWork W2016101198 @default.
- W2037223075 hasRelatedWork W2016225441 @default.
- W2037223075 hasRelatedWork W2040191638 @default.
- W2037223075 hasRelatedWork W2053424985 @default.
- W2037223075 hasRelatedWork W2380360044 @default.
- W2037223075 hasRelatedWork W2388957262 @default.
- W2037223075 hasRelatedWork W2389737778 @default.
- W2037223075 hasRelatedWork W2402632321 @default.
- W2037223075 hasRelatedWork W2903677867 @default.
- W2037223075 hasVolume "88" @default.
- W2037223075 isParatext "false" @default.
- W2037223075 isRetracted "false" @default.
- W2037223075 magId "2037223075" @default.
- W2037223075 workType "article" @default.