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- W2037226713 abstract "A procedure for immobilization of well-defined quantities of oligodeoxyribonucleotides (ODNs) to a versatile nylon support is described. The solid support, a nylon-6/6 bead, is covalently coated with poly(ethyleneimine) to provide a reactive spacer-arm for attachment of ODNs. 5'-Aminohexyl-tailed ODNs are selectively activated using 2,4,6-trichloro-1,3,5-triazine (cyanuric chloride) and then covalently attached to the bead via the triazine moiety. The modified nylon support has a low level of binding of nonspecific nucleic acid and efficiently captures both RNA and DNA targets." @default.
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- W2037226713 date "1991-01-01" @default.
- W2037226713 modified "2023-09-25" @default.
- W2037226713 title "A versatile solid support system for oligodeoxynucleotide probe-based hybridization assays" @default.
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- W2037226713 doi "https://doi.org/10.1093/nar/19.12.3345" @default.
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