FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037262024> ?p ?o ?g. }

• W2037262024 endingPage "10236" @default.
• W2037262024 startingPage "10232" @default.
• W2037262024 abstract "In Saccharomyces cerevisiae, FAS1, FAS2, and FAS3 are the genes involved in saturated fatty acid biosynthesis. The enzymatic activities of both fatty acid synthase (FAS) and acetyl-CoA carboxylase are reduced 2- to 3-fold when yeast cells are grown in the presence of exogenous fatty acids. The mRNA levels of the FAS genes are correspondingly lower under repressive conditions. Expression of the FAS-lacZ reporter gene is also regulated by fatty acids. When a FAS2 multicopy plasmid is present in the cells, expression of both FAS1 and FAS3 increases. Thus, the FAS genes are coordinately regulated. Deletion analyses of the regulatory regions of FAS1 and FAS2 revealed common regulatory sequences. These include the GGCCAAAAAC and AGCCAAGCA sequences that have a common GCCAA core sequence and the UASINO (upstream activation sequence). Derepression of the FAS genes in the absence of exogenous inositol is not observed when UASINO is mutated, indicating that this cis element is a positive regulator of these genes. The GCCAA elements and UASINO act synergistically for optimal expression of the FAS genes." @default.
• W2037262024 created "2016-06-24" @default.
• W2037262024 creator A5014635205 @default.
• W2037262024 date "1992-11-01" @default.
• W2037262024 modified "2023-09-23" @default.
• W2037262024 title "Coordinated regulation and inositol-mediated and fatty acid-mediated repression of fatty acid synthase genes in Saccharomyces cerevisiae." @default.
• W2037262024 cites W1485774101 @default.
• W2037262024 cites W1487196602 @default.
• W2037262024 cites W1487733459 @default.
• W2037262024 cites W1520959004 @default.
• W2037262024 cites W1523834996 @default.
• W2037262024 cites W1563242526 @default.
• W2037262024 cites W1566478858 @default.
• W2037262024 cites W1606153755 @default.
• W2037262024 cites W1755978981 @default.
• W2037262024 cites W1776778875 @default.
• W2037262024 cites W1790188457 @default.
• W2037262024 cites W1859876210 @default.
• W2037262024 cites W1907585328 @default.
• W2037262024 cites W1973782344 @default.
• W2037262024 cites W1975740535 @default.
• W2037262024 cites W1986024822 @default.
• W2037262024 cites W1988239660 @default.
• W2037262024 cites W2002173318 @default.
• W2037262024 cites W2002804418 @default.
• W2037262024 cites W2003798106 @default.
• W2037262024 cites W2018289835 @default.
• W2037262024 cites W2032118018 @default.
• W2037262024 cites W2058256157 @default.
• W2037262024 cites W2066321210 @default.
• W2037262024 cites W2070098352 @default.
• W2037262024 cites W2077077811 @default.
• W2037262024 cites W2083124591 @default.
• W2037262024 cites W2083170742 @default.
• W2037262024 cites W2091663340 @default.
• W2037262024 cites W2100837269 @default.
• W2037262024 cites W2110576629 @default.
• W2037262024 cites W2114185189 @default.
• W2037262024 cites W2128635872 @default.
• W2037262024 cites W2130755410 @default.
• W2037262024 cites W2138270253 @default.
• W2037262024 cites W2152374368 @default.
• W2037262024 cites W2283018830 @default.
• W2037262024 cites W41914561 @default.
• W2037262024 cites W968249938 @default.
• W2037262024 doi "https://doi.org/10.1073/pnas.89.21.10232" @default.
• W2037262024 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/50312" @default.
• W2037262024 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1359536" @default.
• W2037262024 hasPublicationYear "1992" @default.
• W2037262024 type Work @default.
• W2037262024 sameAs 2037262024 @default.
• W2037262024 citedByCount "72" @default.
• W2037262024 countsByYear W20372620242012 @default.
• W2037262024 countsByYear W20372620242013 @default.
• W2037262024 countsByYear W20372620242014 @default.
• W2037262024 countsByYear W20372620242015 @default.
• W2037262024 countsByYear W20372620242016 @default.
• W2037262024 countsByYear W20372620242017 @default.
• W2037262024 countsByYear W20372620242018 @default.
• W2037262024 countsByYear W20372620242019 @default.
• W2037262024 countsByYear W20372620242020 @default.
• W2037262024 countsByYear W20372620242021 @default.
• W2037262024 countsByYear W20372620242022 @default.
• W2037262024 crossrefType "journal-article" @default.
• W2037262024 hasAuthorship W2037262024A5014635205 @default.
• W2037262024 hasBestOaLocation W20372620241 @default.
• W2037262024 hasConcept C104317684 @default.
• W2037262024 hasConcept C140137476 @default.
• W2037262024 hasConcept C150194340 @default.
• W2037262024 hasConcept C153911025 @default.
• W2037262024 hasConcept C161733203 @default.
• W2037262024 hasConcept C181199279 @default.
• W2037262024 hasConcept C186310378 @default.
• W2037262024 hasConcept C21592294 @default.
• W2037262024 hasConcept C2776941171 @default.
• W2037262024 hasConcept C2777576037 @default.
• W2037262024 hasConcept C2779318131 @default.
• W2037262024 hasConcept C33498276 @default.
• W2037262024 hasConcept C48289651 @default.
• W2037262024 hasConcept C543025807 @default.
• W2037262024 hasConcept C55493867 @default.
• W2037262024 hasConcept C73766848 @default.
• W2037262024 hasConcept C86803240 @default.
• W2037262024 hasConceptScore W2037262024C104317684 @default.
• W2037262024 hasConceptScore W2037262024C140137476 @default.
• W2037262024 hasConceptScore W2037262024C150194340 @default.
• W2037262024 hasConceptScore W2037262024C153911025 @default.
• W2037262024 hasConceptScore W2037262024C161733203 @default.
• W2037262024 hasConceptScore W2037262024C181199279 @default.
• W2037262024 hasConceptScore W2037262024C186310378 @default.
• W2037262024 hasConceptScore W2037262024C21592294 @default.
• W2037262024 hasConceptScore W2037262024C2776941171 @default.
• W2037262024 hasConceptScore W2037262024C2777576037 @default.
• W2037262024 hasConceptScore W2037262024C2779318131 @default.
• W2037262024 hasConceptScore W2037262024C33498276 @default.
• W2037262024 hasConceptScore W2037262024C48289651 @default.
• W2037262024 hasConceptScore W2037262024C543025807 @default.
• W2037262024 hasConceptScore W2037262024C55493867 @default.

• next