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• W2037262435 endingPage "1242" @default.
• W2037262435 startingPage "1236" @default.
• W2037262435 abstract "Lead contamination is a serious environmental problem with toxic effects in human. Here, we developed a simple and sensitive sensing method employing ATTO 647N/aptamer-SWNT ensemble for detection of Pb2+. This method is based on the super quenching capability of single-walled carbon nanotubes (SWNTs), high affinity of the aptamer toward Pb2+ and different propensities of ATTO 647N-aptamer and ATTO 647N-aptamer/Pb2+ complex for adsorption on SWNTs. In the absence of Pb2+, the fluorescence of ATTO 647N-aptamer is efficiently quenched by SWNTs. Upon addition of Pb2+, the aptamer binds to its target, leading to the formation of a G-quadruplex/Pb2+ complex and does not interact with SWNTs and ATTO 647N-aptamer starts fluorescing. This sensor exhibited a high selectivity toward Pb2+ and a limit of detection (LOD) as low as 0.42 nM was obtained. Also this sensor could be applied for detection of Pb2+ ions in tap water and biological sample like serum with high sensitivity." @default.
• W2037262435 created "2016-06-24" @default.
• W2037262435 creator A5005226800 @default.
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• W2037262435 date "2014-05-01" @default.
• W2037262435 modified "2023-10-16" @default.
• W2037262435 title "Ultrasensitive detection of lead (II) based on fluorescent aptamer-functionalized carbon nanotubes" @default.
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• W2037262435 doi "https://doi.org/10.1016/j.etap.2014.04.020" @default.
• W2037262435 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24835552" @default.
• W2037262435 hasPublicationYear "2014" @default.
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