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- W2037292735 abstract "In 1949, Reiss and Doherty<sup>1</sup>reported on the beneficial effect of Podophyllum resin ointment in the treatment of ringworm of the scalp. Preliminary clinical trials with this agent by us in scalp infections due to Microsporon audouini yielded apparently encouraging results. Our subsequent controlled studies, with 0.2% podophyllin in carbowax<sup>®</sup>applied twice daily, showed that our initial enthusiasm was unwarranted. In three cases of our earlier series, an interesting form of alopecia developed during treatment. This was assumed to be a toxic effect of the podophyllin, as noted by Goldman,<sup>2</sup>but efforts to understand its mechanism, to control the hair loss, or to use this as a therapeutic measure have been unsuccessful. In none of the children studied was there any evidence of systemic toxic reaction. <h3>REPORT OF A CASE</h3> B. D., a 5-year-old Negro boy, was seen on July 12, 1949, in the Dermatology Clinic of" @default.
- W2037292735 created "2016-06-24" @default.
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- W2037292735 date "1952-05-17" @default.
- W2037292735 modified "2023-09-26" @default.
- W2037292735 title "INEFFECTIVENESS AND TOXICITY OF PODOPHYLLIN IN TREATMENT OF TINEA CAPITIS" @default.
- W2037292735 cites W13059885 @default.
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- W2037292735 doi "https://doi.org/10.1001/jama.1952.72930200004011a" @default.
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