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• W2037331165 abstract "The bioaccumulation and maternal transfer of 2,2',4,4'-tetrabromodiphenyl ether (PBDE 47) were investigated in the marine medaka (Oryzias melastigma) following dietary exposure, in which PBDE 47 was bioencapsulated into brine shrimp (Artemia sp.) and fed daily to male-female pairs of medaka. In the accumulation experiment, each 2-month-old (pre-breeding) medaka were provided with dietary PBDE 47 at 1.3±0.2 μg/day for 21 days. Growth-corrected concentrations of PBDE 47 in the medaka increased over the 21 days of exposure and there were no significant differences between males and females at any of the sampling times. Final concentrations were similar for males and females after 21 days (230±30 and 250±30 μgg(-1) wet weight, respectively), accounting for 84-100% of the PBDE 47 provided in the diet. In the maternal transfer experiment, 3-month-old (breeding) medaka were provided with dietary PBDE 47 at 1.2±0.2 μg/day for 18 days, and reached body concentrations of 76±3 (males) and 61±6 (females)μgg(-1) wet weight. Female growth-corrected PBDE 47 concentrations were significantly lower than males by day 12 (P<0.05), and egg PBDE 47 concentrations were up to 25 ng/egg by day 18. Our results showed that maternal transfer is an important offloading mechanism for female fish. The fact that lipid normalized egg:female PBDE ratios did not significantly deviate from 1 further indicated that the maternal transfer of PBDE 47 is associated with lipid mobilization during egg production." @default.
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• W2037331165 date "2011-06-01" @default.
• W2037331165 modified "2023-10-02" @default.
• W2037331165 title "Bioaccumulation and maternal transfer of PBDE 47 in the marine medaka (Oryzias melastigma) following dietary exposure" @default.
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• W2037331165 doi "https://doi.org/10.1016/j.aquatox.2011.02.021" @default.
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