FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037334368> ?p ?o ?g. }

• W2037334368 endingPage "1244" @default.
• W2037334368 startingPage "1238" @default.
• W2037334368 abstract "The discovery, structure-based design, synthesis, and optimization of NIK inhibitors are described. Our work began with an HTS hit, imidazopyridinyl pyrimidinamine 1. We utilized homology modeling and conformational analysis to optimize the indole scaffold leading to the discovery of novel and potent conformationally constrained inhibitors such as compounds 25 and 28. Compounds 25 and 31 were co-crystallized with NIK kinase domain to provide structural insights." @default.
• W2037334368 created "2016-06-24" @default.
• W2037334368 creator A5004127240 @default.
• W2037334368 creator A5006094386 @default.
• W2037334368 creator A5016700682 @default.
• W2037334368 creator A5021355436 @default.
• W2037334368 creator A5021597292 @default.
• W2037334368 creator A5036125002 @default.
• W2037334368 creator A5037710288 @default.
• W2037334368 creator A5040988713 @default.
• W2037334368 creator A5043897916 @default.
• W2037334368 creator A5044652553 @default.
• W2037334368 creator A5044698164 @default.
• W2037334368 creator A5047251484 @default.
• W2037334368 creator A5054284746 @default.
• W2037334368 creator A5057637884 @default.
• W2037334368 creator A5058323090 @default.
• W2037334368 creator A5070110960 @default.
• W2037334368 creator A5080468748 @default.
• W2037334368 creator A5089560159 @default.
• W2037334368 creator A5090393581 @default.
• W2037334368 date "2013-03-01" @default.
• W2037334368 modified "2023-10-03" @default.
• W2037334368 title "Inhibiting NF-κB-inducing kinase (NIK): Discovery, structure-based design, synthesis, structure–activity relationship, and co-crystal structures" @default.
• W2037334368 cites W1973562447 @default.
• W2037334368 cites W1974533337 @default.
• W2037334368 cites W1987531976 @default.
• W2037334368 cites W1988502798 @default.
• W2037334368 cites W2023724309 @default.
• W2037334368 cites W2028330103 @default.
• W2037334368 cites W2034371559 @default.
• W2037334368 cites W2034802710 @default.
• W2037334368 cites W2057670039 @default.
• W2037334368 cites W2058571113 @default.
• W2037334368 cites W2059237280 @default.
• W2037334368 cites W2060019843 @default.
• W2037334368 cites W2063987509 @default.
• W2037334368 cites W2072380594 @default.
• W2037334368 cites W2075941313 @default.
• W2037334368 cites W2081413298 @default.
• W2037334368 cites W2085144387 @default.
• W2037334368 cites W2092735972 @default.
• W2037334368 cites W2094863064 @default.
• W2037334368 cites W2101580628 @default.
• W2037334368 cites W2127971170 @default.
• W2037334368 cites W2135668656 @default.
• W2037334368 cites W2152330468 @default.
• W2037334368 cites W2159259228 @default.
• W2037334368 cites W2166022914 @default.
• W2037334368 cites W2416455403 @default.
• W2037334368 cites W2951576576 @default.
• W2037334368 cites W2952469622 @default.
• W2037334368 doi "https://doi.org/10.1016/j.bmcl.2013.01.012" @default.
• W2037334368 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23374866" @default.
• W2037334368 hasPublicationYear "2013" @default.
• W2037334368 type Work @default.
• W2037334368 sameAs 2037334368 @default.
• W2037334368 citedByCount "52" @default.
• W2037334368 countsByYear W20373343682013 @default.
• W2037334368 countsByYear W20373343682014 @default.
• W2037334368 countsByYear W20373343682015 @default.
• W2037334368 countsByYear W20373343682016 @default.
• W2037334368 countsByYear W20373343682017 @default.
• W2037334368 countsByYear W20373343682018 @default.
• W2037334368 countsByYear W20373343682019 @default.
• W2037334368 countsByYear W20373343682020 @default.
• W2037334368 countsByYear W20373343682021 @default.
• W2037334368 countsByYear W20373343682022 @default.
• W2037334368 countsByYear W20373343682023 @default.
• W2037334368 crossrefType "journal-article" @default.
• W2037334368 hasAuthorship W2037334368A5004127240 @default.
• W2037334368 hasAuthorship W2037334368A5006094386 @default.
• W2037334368 hasAuthorship W2037334368A5016700682 @default.
• W2037334368 hasAuthorship W2037334368A5021355436 @default.
• W2037334368 hasAuthorship W2037334368A5021597292 @default.
• W2037334368 hasAuthorship W2037334368A5036125002 @default.
• W2037334368 hasAuthorship W2037334368A5037710288 @default.
• W2037334368 hasAuthorship W2037334368A5040988713 @default.
• W2037334368 hasAuthorship W2037334368A5043897916 @default.
• W2037334368 hasAuthorship W2037334368A5044652553 @default.
• W2037334368 hasAuthorship W2037334368A5044698164 @default.
• W2037334368 hasAuthorship W2037334368A5047251484 @default.
• W2037334368 hasAuthorship W2037334368A5054284746 @default.
• W2037334368 hasAuthorship W2037334368A5057637884 @default.
• W2037334368 hasAuthorship W2037334368A5058323090 @default.
• W2037334368 hasAuthorship W2037334368A5070110960 @default.
• W2037334368 hasAuthorship W2037334368A5080468748 @default.
• W2037334368 hasAuthorship W2037334368A5089560159 @default.
• W2037334368 hasAuthorship W2037334368A5090393581 @default.
• W2037334368 hasConcept C104317684 @default.
• W2037334368 hasConcept C115624301 @default.
• W2037334368 hasConcept C143065580 @default.
• W2037334368 hasConcept C169627665 @default.
• W2037334368 hasConcept C178910836 @default.
• W2037334368 hasConcept C181199279 @default.
• W2037334368 hasConcept C184235292 @default.
• W2037334368 hasConcept C185592680 @default.
• W2037334368 hasConcept C192527728 @default.

• next