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• W2037432015 abstract "Tóth L., Karcsú S., Poberai M. & Sávay Gy. (1981) Neuropathology and Applied Neurobiology 7, 399–410 A light and electron microscopic histochemical study on the mechanism of DFP-induced acute and subacute myopathy The histochemical changes occuring in association with the development of acute and subacute myopathy have been studied in the rat diaphragm 30 min-48 h after a single i.p. injection of 1–82 mg/kg of the irreversible cholinesterase inhibitor organophosphate, diisopropylfluorophosphate (DFP). In addition to a considerable inhibition of the AChE activity of the motor end-plates, accumulation of ionic Ca2+ and an increase in neutral protease activity in the subjunctional sarcoplasm have been demonstrated. A temporal and causal relationship has been established between the histochemical changes and the development of the ultrastructural signs of myopathy." @default.
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• W2037432015 date "1981-09-01" @default.
• W2037432015 modified "2023-10-14" @default.
• W2037432015 title "A LIGHT AND ELECTRON MICROSCOPIC HISTOCHEMICAL STUDY ON THE MECHANISM OF DFP-INDUCED ACUTE AND SUBACUTE MYOPATHY" @default.
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• W2037432015 doi "https://doi.org/10.1111/j.1365-2990.1981.tb00241.x" @default.
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