Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037442654> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2037442654 endingPage "26" @default.
- W2037442654 startingPage "17" @default.
- W2037442654 abstract "A small percentage of retinal ganglion cells (RGCs) express melanopsin and are intrinsically photosensitive (ipRGCs). Whether light can affect the development of ipRGCs is not clear. In the rat retina, we found constant light exposure during the first postnatal week significantly increased the number of melanopsin immunopositive ipRGCs. This increase was durable and specific for melanopsin immunopositive ipRGCs. BrdU labeling showed no proliferation of the melanopsin immunopositive ipRGCs during constant light exposure. Retrograde labeling from the superior colliculus showed that no other types of RGCs were induced to express melanopsin. Light exposure was effective in increasing melanopsin immunopositive ipRGCs only when it coincided with the apoptotic phase of RGC development. However, daily intravitreous injection of tetrodotoxin, blocking action potentials, abolished the light induced increase of melanopsin immunopositive ipRGCs. These findings indicate that early light exposure can increase the number of melanopsin immunopositive ipRGCs through a process dependent on intrinsic photosensitive spiking activity. Furthermore, the increase of melanopsin immunopositive ipRGCs is potentially induced by apoptosis suppression in ipRGCs or enhanced expression of melanopsin." @default.
- W2037442654 created "2016-06-24" @default.
- W2037442654 creator A5025691011 @default.
- W2037442654 creator A5026906414 @default.
- W2037442654 creator A5026914217 @default.
- W2037442654 creator A5035712664 @default.
- W2037442654 creator A5054771496 @default.
- W2037442654 creator A5081729246 @default.
- W2037442654 date "2013-06-01" @default.
- W2037442654 modified "2023-10-15" @default.
- W2037442654 title "Controlling the number of melanopsin-containing retinal ganglion cells by early light exposure" @default.
- W2037442654 cites W1488048016 @default.
- W2037442654 cites W1511847553 @default.
- W2037442654 cites W1964365138 @default.
- W2037442654 cites W1971524741 @default.
- W2037442654 cites W1974899081 @default.
- W2037442654 cites W1984155636 @default.
- W2037442654 cites W1999659875 @default.
- W2037442654 cites W2009077913 @default.
- W2037442654 cites W2014028088 @default.
- W2037442654 cites W2015340853 @default.
- W2037442654 cites W2026513473 @default.
- W2037442654 cites W2035853180 @default.
- W2037442654 cites W2036239753 @default.
- W2037442654 cites W2038520118 @default.
- W2037442654 cites W2042179612 @default.
- W2037442654 cites W2049690253 @default.
- W2037442654 cites W2056888759 @default.
- W2037442654 cites W2061683639 @default.
- W2037442654 cites W2066556283 @default.
- W2037442654 cites W2066674350 @default.
- W2037442654 cites W2073148060 @default.
- W2037442654 cites W2073465590 @default.
- W2037442654 cites W2075158314 @default.
- W2037442654 cites W2083054113 @default.
- W2037442654 cites W2091088099 @default.
- W2037442654 cites W2107083462 @default.
- W2037442654 cites W2111530177 @default.
- W2037442654 cites W2116354730 @default.
- W2037442654 cites W2122268695 @default.
- W2037442654 cites W2130158155 @default.
- W2037442654 cites W2147949992 @default.
- W2037442654 cites W2151131721 @default.
- W2037442654 doi "https://doi.org/10.1016/j.exer.2013.03.011" @default.
- W2037442654 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23541830" @default.
- W2037442654 hasPublicationYear "2013" @default.
- W2037442654 type Work @default.
- W2037442654 sameAs 2037442654 @default.
- W2037442654 citedByCount "5" @default.
- W2037442654 countsByYear W20374426542013 @default.
- W2037442654 countsByYear W20374426542016 @default.
- W2037442654 countsByYear W20374426542017 @default.
- W2037442654 countsByYear W20374426542021 @default.
- W2037442654 crossrefType "journal-article" @default.
- W2037442654 hasAuthorship W2037442654A5025691011 @default.
- W2037442654 hasAuthorship W2037442654A5026906414 @default.
- W2037442654 hasAuthorship W2037442654A5026914217 @default.
- W2037442654 hasAuthorship W2037442654A5035712664 @default.
- W2037442654 hasAuthorship W2037442654A5054771496 @default.
- W2037442654 hasAuthorship W2037442654A5081729246 @default.
- W2037442654 hasConcept C169760540 @default.
- W2037442654 hasConcept C189780591 @default.
- W2037442654 hasConcept C2777093970 @default.
- W2037442654 hasConcept C2777624874 @default.
- W2037442654 hasConcept C3449773 @default.
- W2037442654 hasConcept C38137364 @default.
- W2037442654 hasConcept C86803240 @default.
- W2037442654 hasConceptScore W2037442654C169760540 @default.
- W2037442654 hasConceptScore W2037442654C189780591 @default.
- W2037442654 hasConceptScore W2037442654C2777093970 @default.
- W2037442654 hasConceptScore W2037442654C2777624874 @default.
- W2037442654 hasConceptScore W2037442654C3449773 @default.
- W2037442654 hasConceptScore W2037442654C38137364 @default.
- W2037442654 hasConceptScore W2037442654C86803240 @default.
- W2037442654 hasFunder F4320321001 @default.
- W2037442654 hasFunder F4320335777 @default.
- W2037442654 hasLocation W20374426541 @default.
- W2037442654 hasLocation W20374426542 @default.
- W2037442654 hasOpenAccess W2037442654 @default.
- W2037442654 hasPrimaryLocation W20374426541 @default.
- W2037442654 hasRelatedWork W2045972108 @default.
- W2037442654 hasRelatedWork W2052588363 @default.
- W2037442654 hasRelatedWork W2113150385 @default.
- W2037442654 hasRelatedWork W2116749682 @default.
- W2037442654 hasRelatedWork W2143502943 @default.
- W2037442654 hasRelatedWork W2150393607 @default.
- W2037442654 hasRelatedWork W2194214728 @default.
- W2037442654 hasRelatedWork W2542141653 @default.
- W2037442654 hasRelatedWork W3109924228 @default.
- W2037442654 hasRelatedWork W3163660896 @default.
- W2037442654 hasVolume "111" @default.
- W2037442654 isParatext "false" @default.
- W2037442654 isRetracted "false" @default.
- W2037442654 magId "2037442654" @default.
- W2037442654 workType "article" @default.