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- W2037448910 abstract "Wine yeast strains show a high level of chromosome length polymorphism. This polymorphism is mainly generated by illegitimate recombination mediated by Ty transposons or subtelomeric repeated sequences. We have found, however, that the SSU1-R allele, which confers sulfite resistance to yeast cells, is the product of a reciprocal translocation between chromosomes VIII and XVI due to unequal crossing-over mediated by microhomology between very short sequences on the 5' upstream regions of the SSU1 and ECM34 genes. We also show that this translocation is only present in wine yeast strains, suggesting that the use for millennia of sulfite as a preservative in wine production could have favored its selection. This is the first time that a gross chromosomal rearrangement is shown to be involved in the adaptive evolution of Saccharomyces cerevisiae." @default.
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- W2037448910 date "2002-10-01" @default.
- W2037448910 modified "2023-10-17" @default.
- W2037448910 title "Molecular Characterization of a Chromosomal Rearrangement Involved in the Adaptive Evolution of Yeast Strains" @default.
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- W2037448910 doi "https://doi.org/10.1101/gr.436602" @default.
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