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- W2037456360 abstract "The hypothesis that alphafetoprotein (AFP) could be a constituent of the estradiol receptor in the uterus and brain of the immature mouse has been tested. Cytosols prepared from 2 week-old mice were depleted of AFP by immunoadsorption with a Sepharose-coupled anti-mouse AFP antiserum. Aliquots of these cytosols containing nondetectable levels of APP by RIA were then brought to 0.4 M KC1 to convert 8 S estradiol receptors to the 4–5 S forms, reacted either with anti-AFP or with a control anti-IgG immunoadsorbent, labeled with 3H-estradiol, and centrifuged on glycerol gradients. There was no, or very little, loss of estradiol receptors in the experimental as compared to the control cytosols indicating that APP is not a constituent of the 8 S estradiol receptor." @default.
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- W2037456360 date "1977-11-01" @default.
- W2037456360 modified "2023-09-25" @default.
- W2037456360 title "Alphafetoprotein is not a component of the 8 S estradiol receptor from the immature mouse uterus or brain" @default.
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- W2037456360 doi "https://doi.org/10.1016/0039-128x(77)90060-5" @default.
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