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• W2037480405 abstract "In this study the morphology, physical properties, surface chemical characteristics and microstructure of the Vascugraft® arterial prosthesis have been investigated. This is a novel microporous polyurethane device, recently developed by the company Braun-Melsungen AG in Germany for use as a small calibre arterial substitute. This comparative study included two other synthetic grafts: the Mitrathane® prosthesis, a hydrophilic prototype polyetherurethane urea graft with closed internal pores, and the commercially successful expanded polytetrafluoroethylene reinforced Goretex® prosthesis with an open microporous structure. The Vascugraft® prosthesis contains a network of fused microfibres of varying thickness and orientation which provide open and communicating pores similar in size to those in the Goretex® material. In addition, they extend from one side of the graft wall to the other. As well as having superior longitudinal and radial compliance to the reinforced Goretex ® device, the Vascugraft® prosthesis has more than adequate bursting and suture retention strengths. Through the use of contact angle measurements, electron spectroscopy for chemical analysis, Fourier transform infrared spectroscopy, differential scanning calorimetry and molecular weight analysis by size exclusion chromatography, the surface of the Vascugraft® prosthesis has been shown to be uniquely hydrophobic, as well as containing carbonate groups within an aliphatic polyesterurethane polymer. In addition, variations in micro-phase separation structure of hard and soft segment domains between different sizes and batches of product are marginal. Because of the interesting physical and chemical properties, it is recommended that in vitro biocompatibility and biostability studies be undertaken prior to using the prosthesis in animal or clinical trials." @default.
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• W2037480405 date "1994-06-01" @default.
• W2037480405 modified "2023-10-10" @default.
• W2037480405 title "Morphological, physical and chemical evaluation of the Vascugraft® arterial prosthesis: comparison of a novel polyurethane device with other microporous structures" @default.
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• W2037480405 doi "https://doi.org/10.1016/0142-9612(94)90014-0" @default.
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