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- W2037496736 abstract "Purpose: The purpose of this paper is to discuss lethal midline granuloma (LMG)-nasal natural killer (NK) T-cell lymphoma (LMG-NTL). Methods: Literature review. Results: LMG is a rare entity that usually arises in the nasal cavity, exhibits a male preponderance, and has a wide age range. The majority of LMGs are LMG-NTLs. The optimal treatment of LMG-NTL is unclear and is most likely moderate-dose radiotherapy. The prognosis for patients with LMG-NTL is significantly worse than for patients with other types of head and neck non-Hodgkin lymphomas (NHL). The 5-year survival rate is approximately 20% but may be higher, depending on whether patients with less aggressive forms of NHL are included. Initial local-regional disease progression is the predominant pattern of treatment failure. Late failures after 5 years are uncommon. Conclusions: LMG-NTL is a rare nasal NK/T-cell lymphoma that can be difficult to distinguish from other benign and malignant entities. Its clinical course, however, is extremely aggressive. The patterns of failure suggest a role for more aggressive local-regional treatment, as well as more effective chemotherapy." @default.
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- W2037496736 date "2006-04-01" @default.
- W2037496736 modified "2023-09-25" @default.
- W2037496736 title "Lethal Midline Granuloma-Nasal Natural Killer/T-Cell Lymphoma" @default.
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- W2037496736 doi "https://doi.org/10.1097/01.coc.0000198738.61238.eb" @default.
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