Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037635895> ?p ?o ?g. }
- W2037635895 endingPage "2740" @default.
- W2037635895 startingPage "2729" @default.
- W2037635895 abstract "Using modern echocardiography, we quantified the extent of global myocardial function and perfusion abnormalities in patients with type 2 diabetes and compared this with the hypothetically similar extent of impairments in patients with coronary artery disease (CAD). This case–control study (66 patients) compared four age-matched groups: control, type 2 diabetic, CAD, and diabetic subjects with CAD (DCAD) and left ventricular ejection fraction >50%. CAD patients had 1–2 vessel disease. Diastolic and systolic myocardial velocities were assessed with pulsed tissue Doppler. Global myocardial perfusion was assessed with contrast echocardiography as indices of capillary blood volume and myocardial blood flow at maximal vasodilatation. In CAD and DCAD patients, functional and perfusion parameters were additionally assessed in the territory with a normal coronary angiogram reading, providing a model for comparison with the global data from control and diabetic patients. Comparing diabetic with control subjects, myocardial velocity at early diastole was impaired (8.8±1.8 vs 10.1±1.7 cm/s; p=0.02) and correlated inversely with age, HbA1c and pulse pressure (R 2=0.761). Capillary blood volume (16.6±5.0 vs 24.4±4.9%) and blood flow (56±35 vs 114±40) were decreased (p=0.001). In CAD patients, myocardial velocity at early diastole was similarly decreased (p=0.02). CAD and DCAD patients were receiving more cardiovascular preventive therapy for the same extent of impaired global perfusion as in the less extensively treated diabetes group without CAD (p<0.002), but had superior perfusion of the ‘normal’ coronary territory than that group (p<0.05). In patients with diabetes, global diastolic function and myocardial capillary blood volume and blood flow are impaired to the same extent as in patients with CAD. These impairments could form the basis of new therapeutic concepts." @default.
- W2037635895 created "2016-06-24" @default.
- W2037635895 creator A5011912492 @default.
- W2037635895 creator A5042317808 @default.
- W2037635895 creator A5052325511 @default.
- W2037635895 creator A5065037475 @default.
- W2037635895 creator A5066852526 @default.
- W2037635895 creator A5076814992 @default.
- W2037635895 date "2006-09-21" @default.
- W2037635895 modified "2023-10-18" @default.
- W2037635895 title "Global myocardial perfusion and diastolic function are impaired to a similar extent in patients with type 2 diabetes mellitus and in patients with coronary artery disease—evaluation by contrast echocardiography and pulsed tissue Doppler" @default.
- W2037635895 cites W1530557965 @default.
- W2037635895 cites W1604542334 @default.
- W2037635895 cites W1651088800 @default.
- W2037635895 cites W1971809538 @default.
- W2037635895 cites W1973860737 @default.
- W2037635895 cites W1975039732 @default.
- W2037635895 cites W1975856506 @default.
- W2037635895 cites W1982603629 @default.
- W2037635895 cites W1991514810 @default.
- W2037635895 cites W1995612707 @default.
- W2037635895 cites W1996129022 @default.
- W2037635895 cites W1997287332 @default.
- W2037635895 cites W2003106879 @default.
- W2037635895 cites W2028865557 @default.
- W2037635895 cites W2032943411 @default.
- W2037635895 cites W2043828746 @default.
- W2037635895 cites W2056561246 @default.
- W2037635895 cites W2057755561 @default.
- W2037635895 cites W2058507958 @default.
- W2037635895 cites W2065690651 @default.
- W2037635895 cites W2069830389 @default.
- W2037635895 cites W2070692648 @default.
- W2037635895 cites W2071238433 @default.
- W2037635895 cites W2072659094 @default.
- W2037635895 cites W2083287402 @default.
- W2037635895 cites W2089736652 @default.
- W2037635895 cites W2096096847 @default.
- W2037635895 cites W2100049803 @default.
- W2037635895 cites W2103689416 @default.
- W2037635895 cites W2113155619 @default.
- W2037635895 cites W2113169712 @default.
- W2037635895 cites W2113538204 @default.
- W2037635895 cites W2119171735 @default.
- W2037635895 cites W2125048739 @default.
- W2037635895 cites W2140937253 @default.
- W2037635895 cites W2141222928 @default.
- W2037635895 cites W2146578470 @default.
- W2037635895 cites W2151002896 @default.
- W2037635895 cites W2152772990 @default.
- W2037635895 cites W2158919441 @default.
- W2037635895 cites W2159918504 @default.
- W2037635895 cites W2169015558 @default.
- W2037635895 cites W2529012027 @default.
- W2037635895 cites W2975364463 @default.
- W2037635895 cites W2990123797 @default.
- W2037635895 cites W3015544325 @default.
- W2037635895 cites W4229984599 @default.
- W2037635895 cites W4252437054 @default.
- W2037635895 cites W4300535524 @default.
- W2037635895 cites W95049066 @default.
- W2037635895 cites W2078171881 @default.
- W2037635895 doi "https://doi.org/10.1007/s00125-006-0398-x" @default.
- W2037635895 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17016696" @default.
- W2037635895 hasPublicationYear "2006" @default.
- W2037635895 type Work @default.
- W2037635895 sameAs 2037635895 @default.
- W2037635895 citedByCount "26" @default.
- W2037635895 countsByYear W20376358952012 @default.
- W2037635895 countsByYear W20376358952013 @default.
- W2037635895 countsByYear W20376358952014 @default.
- W2037635895 countsByYear W20376358952016 @default.
- W2037635895 countsByYear W20376358952021 @default.
- W2037635895 countsByYear W20376358952023 @default.
- W2037635895 crossrefType "journal-article" @default.
- W2037635895 hasAuthorship W2037635895A5011912492 @default.
- W2037635895 hasAuthorship W2037635895A5042317808 @default.
- W2037635895 hasAuthorship W2037635895A5052325511 @default.
- W2037635895 hasAuthorship W2037635895A5065037475 @default.
- W2037635895 hasAuthorship W2037635895A5066852526 @default.
- W2037635895 hasAuthorship W2037635895A5076814992 @default.
- W2037635895 hasBestOaLocation W20376358951 @default.
- W2037635895 hasConcept C126322002 @default.
- W2037635895 hasConcept C134018914 @default.
- W2037635895 hasConcept C146957229 @default.
- W2037635895 hasConcept C158846371 @default.
- W2037635895 hasConcept C164705383 @default.
- W2037635895 hasConcept C2778198053 @default.
- W2037635895 hasConcept C2778213512 @default.
- W2037635895 hasConcept C500558357 @default.
- W2037635895 hasConcept C555293320 @default.
- W2037635895 hasConcept C57900726 @default.
- W2037635895 hasConcept C71924100 @default.
- W2037635895 hasConcept C78085059 @default.
- W2037635895 hasConcept C84393581 @default.
- W2037635895 hasConceptScore W2037635895C126322002 @default.
- W2037635895 hasConceptScore W2037635895C134018914 @default.
- W2037635895 hasConceptScore W2037635895C146957229 @default.