Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037646532> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2037646532 endingPage "744" @default.
- W2037646532 startingPage "741" @default.
- W2037646532 abstract "Seventy-five patients with probable Alzheimer's disease were screened for binding of alpha 2 receptors (A2R) to their platelet membranes; the results were compared with 51 age- and sex-matched controls. Receptor binding assays were performed using [3H] Yohimbine as the radioligand. The results showed a higher binding capacity in the demented population as compared to the control group (2.18 +/- 0.15 fmol/mg protein, as compared to 1.73 +/- 0.13, P less than 0.03). This increased binding to platelets in the demented patients was more prominent in demented females: 34% higher binding as compared with female controls (2.06 +/- 0.5 vs 1.54 +/- 0.04). The difference between demented and normal males was less (2.34 +/- 0.05 vs 1.88 +/- 0.05). The results indicate an involvement of the A2R system, either primarily or secondarily, in the disease process. Since there is an overlap between results from the patients with Alzheimer's disease and the normal subjects, A2R may serve as only a supportive marker for Alzheimer's disease." @default.
- W2037646532 created "2016-06-24" @default.
- W2037646532 creator A5011419345 @default.
- W2037646532 creator A5012022294 @default.
- W2037646532 creator A5067884267 @default.
- W2037646532 date "1989-08-01" @default.
- W2037646532 modified "2023-09-23" @default.
- W2037646532 title "Alzheimer's Dementia and Binding to Alpha2Adrenoreceptors in Platelets" @default.
- W2037646532 cites W1973224263 @default.
- W2037646532 cites W1980845432 @default.
- W2037646532 cites W1988240074 @default.
- W2037646532 cites W1991300070 @default.
- W2037646532 cites W2010928495 @default.
- W2037646532 cites W2023333160 @default.
- W2037646532 cites W2024501220 @default.
- W2037646532 cites W2025266169 @default.
- W2037646532 cites W2032046308 @default.
- W2037646532 cites W2056046302 @default.
- W2037646532 cites W2057791111 @default.
- W2037646532 cites W2061034390 @default.
- W2037646532 cites W2061179388 @default.
- W2037646532 cites W2064093411 @default.
- W2037646532 cites W2067987794 @default.
- W2037646532 cites W2069682857 @default.
- W2037646532 cites W2072579639 @default.
- W2037646532 cites W2087773962 @default.
- W2037646532 cites W2090407616 @default.
- W2037646532 cites W2091505182 @default.
- W2037646532 cites W2109350696 @default.
- W2037646532 cites W2145580671 @default.
- W2037646532 cites W2202288132 @default.
- W2037646532 cites W2413507981 @default.
- W2037646532 cites W2415132512 @default.
- W2037646532 cites W975975057 @default.
- W2037646532 doi "https://doi.org/10.1111/j.1532-5415.1989.tb02236.x" @default.
- W2037646532 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2546986" @default.
- W2037646532 hasPublicationYear "1989" @default.
- W2037646532 type Work @default.
- W2037646532 sameAs 2037646532 @default.
- W2037646532 citedByCount "5" @default.
- W2037646532 countsByYear W20376465322014 @default.
- W2037646532 countsByYear W20376465322015 @default.
- W2037646532 crossrefType "journal-article" @default.
- W2037646532 hasAuthorship W2037646532A5011419345 @default.
- W2037646532 hasAuthorship W2037646532A5012022294 @default.
- W2037646532 hasAuthorship W2037646532A5067884267 @default.
- W2037646532 hasConcept C126322002 @default.
- W2037646532 hasConcept C134018914 @default.
- W2037646532 hasConcept C170493617 @default.
- W2037646532 hasConcept C2777427615 @default.
- W2037646532 hasConcept C2779134260 @default.
- W2037646532 hasConcept C2779483572 @default.
- W2037646532 hasConcept C2908647359 @default.
- W2037646532 hasConcept C2909005528 @default.
- W2037646532 hasConcept C502032728 @default.
- W2037646532 hasConcept C67847695 @default.
- W2037646532 hasConcept C71924100 @default.
- W2037646532 hasConcept C89560881 @default.
- W2037646532 hasConcept C99454951 @default.
- W2037646532 hasConceptScore W2037646532C126322002 @default.
- W2037646532 hasConceptScore W2037646532C134018914 @default.
- W2037646532 hasConceptScore W2037646532C170493617 @default.
- W2037646532 hasConceptScore W2037646532C2777427615 @default.
- W2037646532 hasConceptScore W2037646532C2779134260 @default.
- W2037646532 hasConceptScore W2037646532C2779483572 @default.
- W2037646532 hasConceptScore W2037646532C2908647359 @default.
- W2037646532 hasConceptScore W2037646532C2909005528 @default.
- W2037646532 hasConceptScore W2037646532C502032728 @default.
- W2037646532 hasConceptScore W2037646532C67847695 @default.
- W2037646532 hasConceptScore W2037646532C71924100 @default.
- W2037646532 hasConceptScore W2037646532C89560881 @default.
- W2037646532 hasConceptScore W2037646532C99454951 @default.
- W2037646532 hasIssue "8" @default.
- W2037646532 hasLocation W20376465321 @default.
- W2037646532 hasLocation W20376465322 @default.
- W2037646532 hasOpenAccess W2037646532 @default.
- W2037646532 hasPrimaryLocation W20376465321 @default.
- W2037646532 hasRelatedWork W1968117641 @default.
- W2037646532 hasRelatedWork W2034583712 @default.
- W2037646532 hasRelatedWork W2037646532 @default.
- W2037646532 hasRelatedWork W2063619316 @default.
- W2037646532 hasRelatedWork W2074821979 @default.
- W2037646532 hasRelatedWork W2169225653 @default.
- W2037646532 hasRelatedWork W2223320408 @default.
- W2037646532 hasRelatedWork W313460363 @default.
- W2037646532 hasRelatedWork W136979860 @default.
- W2037646532 hasRelatedWork W2199183705 @default.
- W2037646532 hasVolume "37" @default.
- W2037646532 isParatext "false" @default.
- W2037646532 isRetracted "false" @default.
- W2037646532 magId "2037646532" @default.
- W2037646532 workType "article" @default.