Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037648548> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2037648548 endingPage "2308" @default.
- W2037648548 startingPage "2302" @default.
- W2037648548 abstract "The assembly of chick brain microtubule protein in a NaCl-supplemented buffer has been examined with respect to nucleation and the subsequent elongation as a function of the nucleotide (GTP vs 2'dGTP), and the protein and nucleotide concentrations. The kinetics suggest that unassembled tubulin can exist in two conformational states (termed Tu1,GTP and Tu2,GIP when GTP is bound to the exchangeable site), with Tu1,GTP contributing to nucleation and Tu2,GTP participating in elongation. The extent of self-nucleation is proposed to be determined, in part, by the rate constant governing this conformational change. This analysis contrasts with that of earlier studies, which concluded that the number of subunits interacting to form an effective nucleus could be estimated from the dependency of self-nucleation on the initial concentration of unassembled tubulin." @default.
- W2037648548 created "2016-06-24" @default.
- W2037648548 creator A5006575429 @default.
- W2037648548 creator A5024600536 @default.
- W2037648548 date "1995-02-12" @default.
- W2037648548 modified "2023-09-26" @default.
- W2037648548 title "In Vitro Assembly of Microtubule Protein with GTP and 2'dGTP: Kinetic Evidence for a Preassembly Conformational Change" @default.
- W2037648548 doi "https://doi.org/10.1021/bi00007a026" @default.
- W2037648548 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7857941" @default.
- W2037648548 hasPublicationYear "1995" @default.
- W2037648548 type Work @default.
- W2037648548 sameAs 2037648548 @default.
- W2037648548 citedByCount "3" @default.
- W2037648548 crossrefType "journal-article" @default.
- W2037648548 hasAuthorship W2037648548A5006575429 @default.
- W2037648548 hasAuthorship W2037648548A5024600536 @default.
- W2037648548 hasConcept C104317684 @default.
- W2037648548 hasConcept C10447061 @default.
- W2037648548 hasConcept C112950240 @default.
- W2037648548 hasConcept C118716 @default.
- W2037648548 hasConcept C121332964 @default.
- W2037648548 hasConcept C12554922 @default.
- W2037648548 hasConcept C148898269 @default.
- W2037648548 hasConcept C1491633281 @default.
- W2037648548 hasConcept C178790620 @default.
- W2037648548 hasConcept C181199279 @default.
- W2037648548 hasConcept C185592680 @default.
- W2037648548 hasConcept C191897082 @default.
- W2037648548 hasConcept C192562407 @default.
- W2037648548 hasConcept C20418707 @default.
- W2037648548 hasConcept C2777339483 @default.
- W2037648548 hasConcept C29537977 @default.
- W2037648548 hasConcept C33947775 @default.
- W2037648548 hasConcept C512185932 @default.
- W2037648548 hasConcept C55493867 @default.
- W2037648548 hasConcept C61048295 @default.
- W2037648548 hasConcept C62520636 @default.
- W2037648548 hasConcept C8010536 @default.
- W2037648548 hasConcept C84425145 @default.
- W2037648548 hasConcept C86803240 @default.
- W2037648548 hasConcept C94921385 @default.
- W2037648548 hasConcept C95444343 @default.
- W2037648548 hasConceptScore W2037648548C104317684 @default.
- W2037648548 hasConceptScore W2037648548C10447061 @default.
- W2037648548 hasConceptScore W2037648548C112950240 @default.
- W2037648548 hasConceptScore W2037648548C118716 @default.
- W2037648548 hasConceptScore W2037648548C121332964 @default.
- W2037648548 hasConceptScore W2037648548C12554922 @default.
- W2037648548 hasConceptScore W2037648548C148898269 @default.
- W2037648548 hasConceptScore W2037648548C1491633281 @default.
- W2037648548 hasConceptScore W2037648548C178790620 @default.
- W2037648548 hasConceptScore W2037648548C181199279 @default.
- W2037648548 hasConceptScore W2037648548C185592680 @default.
- W2037648548 hasConceptScore W2037648548C191897082 @default.
- W2037648548 hasConceptScore W2037648548C192562407 @default.
- W2037648548 hasConceptScore W2037648548C20418707 @default.
- W2037648548 hasConceptScore W2037648548C2777339483 @default.
- W2037648548 hasConceptScore W2037648548C29537977 @default.
- W2037648548 hasConceptScore W2037648548C33947775 @default.
- W2037648548 hasConceptScore W2037648548C512185932 @default.
- W2037648548 hasConceptScore W2037648548C55493867 @default.
- W2037648548 hasConceptScore W2037648548C61048295 @default.
- W2037648548 hasConceptScore W2037648548C62520636 @default.
- W2037648548 hasConceptScore W2037648548C8010536 @default.
- W2037648548 hasConceptScore W2037648548C84425145 @default.
- W2037648548 hasConceptScore W2037648548C86803240 @default.
- W2037648548 hasConceptScore W2037648548C94921385 @default.
- W2037648548 hasConceptScore W2037648548C95444343 @default.
- W2037648548 hasIssue "7" @default.
- W2037648548 hasLocation W20376485481 @default.
- W2037648548 hasLocation W20376485482 @default.
- W2037648548 hasOpenAccess W2037648548 @default.
- W2037648548 hasPrimaryLocation W20376485481 @default.
- W2037648548 hasRelatedWork W1555174091 @default.
- W2037648548 hasRelatedWork W1970956816 @default.
- W2037648548 hasRelatedWork W2002652733 @default.
- W2037648548 hasRelatedWork W2057106900 @default.
- W2037648548 hasRelatedWork W2060582652 @default.
- W2037648548 hasRelatedWork W2063181688 @default.
- W2037648548 hasRelatedWork W2087247491 @default.
- W2037648548 hasRelatedWork W2089886351 @default.
- W2037648548 hasRelatedWork W2091919215 @default.
- W2037648548 hasRelatedWork W3044848107 @default.
- W2037648548 hasVolume "34" @default.
- W2037648548 isParatext "false" @default.
- W2037648548 isRetracted "false" @default.
- W2037648548 magId "2037648548" @default.
- W2037648548 workType "article" @default.