Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037648717> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2037648717 endingPage "190" @default.
- W2037648717 startingPage "187" @default.
- W2037648717 abstract "Abstract Background: Antimicrobial resistance of Helicobacter pylori is a growing problem in clinical practice, particularly clarithromycin resistance. The aim of the present study was therefore to investigate the prevalence of H. pylori resistance to antimicrobial agents in Japanese children. Methods: A total of 61 H. pylori strains isolated from children (mean age, 12.6 years; range, 4–18 years) between 1999 and 2007 were studied for primary antimicrobial resistance, using a microdilution method. In addition, the eradication rate with lansoprazole‐based triple regimens was determined. Results: The overall resistance rate of clarithromycin, amoxicillin and metronidazole was 36.1%, 0% and 14.8%, respectively. Resistance to both clarithromycin and metronidazole was detected in 6.6% of the strains. The rate of clarithromycin‐resistant strains was 32.4% from 1999 to 2002 and 40.7% from 2003 to 2007, and clarithromycin minimum inhibitory concentration at which 90% of the isolates were inhibited (MIC 90 ) increased fourfold from 1999–2002 to 2003–2007, with all clarithromycin‐resistant strains showing low‐level resistance. Metronidazole resistance rates were not different between these two study periods. Regimens involving amoxicillin and clarithromycin ( n = 49) had a higher eradication rate in clarithromycin‐susceptible strains (97.1%) than in the resistant strains (57.1%; P < 0.001). There was no difference in the eradication rate between 7 day and 10 or 14 day courses of the regimens ( P = 0.53). The regimen with amoxicillin and metronidazole produced successful eradication in all nine patients with clarithromycin‐resistant strains. Conclusions: Clarithromycin resistance of H. pylori is high, and triple regimen treatment containing clarithromycin should be decided based on susceptibility to the agent." @default.
- W2037648717 created "2016-06-24" @default.
- W2037648717 creator A5003492342 @default.
- W2037648717 creator A5015913121 @default.
- W2037648717 date "2010-03-25" @default.
- W2037648717 modified "2023-10-16" @default.
- W2037648717 title "Primary antimicrobial resistance of <i>Helicobacter pylori</i> in children during the past 9 years" @default.
- W2037648717 cites W1642222373 @default.
- W2037648717 cites W1968198330 @default.
- W2037648717 cites W2015855307 @default.
- W2037648717 cites W2030469355 @default.
- W2037648717 cites W2041279633 @default.
- W2037648717 cites W2052020843 @default.
- W2037648717 cites W2052998908 @default.
- W2037648717 cites W2057597061 @default.
- W2037648717 cites W2060752995 @default.
- W2037648717 cites W2069378448 @default.
- W2037648717 cites W2101940621 @default.
- W2037648717 cites W2132269037 @default.
- W2037648717 cites W2133804568 @default.
- W2037648717 cites W2141303491 @default.
- W2037648717 cites W2152000612 @default.
- W2037648717 cites W2153418611 @default.
- W2037648717 cites W2168001292 @default.
- W2037648717 cites W2170232574 @default.
- W2037648717 cites W2171319113 @default.
- W2037648717 doi "https://doi.org/10.1111/j.1442-200x.2009.02915.x" @default.
- W2037648717 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19563459" @default.
- W2037648717 hasPublicationYear "2010" @default.
- W2037648717 type Work @default.
- W2037648717 sameAs 2037648717 @default.
- W2037648717 citedByCount "37" @default.
- W2037648717 countsByYear W20376487172012 @default.
- W2037648717 countsByYear W20376487172013 @default.
- W2037648717 countsByYear W20376487172014 @default.
- W2037648717 countsByYear W20376487172015 @default.
- W2037648717 countsByYear W20376487172016 @default.
- W2037648717 countsByYear W20376487172017 @default.
- W2037648717 countsByYear W20376487172018 @default.
- W2037648717 countsByYear W20376487172019 @default.
- W2037648717 countsByYear W20376487172020 @default.
- W2037648717 countsByYear W20376487172022 @default.
- W2037648717 crossrefType "journal-article" @default.
- W2037648717 hasAuthorship W2037648717A5003492342 @default.
- W2037648717 hasAuthorship W2037648717A5015913121 @default.
- W2037648717 hasConcept C114851261 @default.
- W2037648717 hasConcept C126322002 @default.
- W2037648717 hasConcept C2776409635 @default.
- W2037648717 hasConcept C2776962512 @default.
- W2037648717 hasConcept C2777396551 @default.
- W2037648717 hasConcept C2778715759 @default.
- W2037648717 hasConcept C2779708577 @default.
- W2037648717 hasConcept C2781413609 @default.
- W2037648717 hasConcept C4937899 @default.
- W2037648717 hasConcept C501593827 @default.
- W2037648717 hasConcept C71924100 @default.
- W2037648717 hasConcept C81396022 @default.
- W2037648717 hasConcept C86803240 @default.
- W2037648717 hasConcept C89423630 @default.
- W2037648717 hasConcept C90924648 @default.
- W2037648717 hasConcept C94665300 @default.
- W2037648717 hasConceptScore W2037648717C114851261 @default.
- W2037648717 hasConceptScore W2037648717C126322002 @default.
- W2037648717 hasConceptScore W2037648717C2776409635 @default.
- W2037648717 hasConceptScore W2037648717C2776962512 @default.
- W2037648717 hasConceptScore W2037648717C2777396551 @default.
- W2037648717 hasConceptScore W2037648717C2778715759 @default.
- W2037648717 hasConceptScore W2037648717C2779708577 @default.
- W2037648717 hasConceptScore W2037648717C2781413609 @default.
- W2037648717 hasConceptScore W2037648717C4937899 @default.
- W2037648717 hasConceptScore W2037648717C501593827 @default.
- W2037648717 hasConceptScore W2037648717C71924100 @default.
- W2037648717 hasConceptScore W2037648717C81396022 @default.
- W2037648717 hasConceptScore W2037648717C86803240 @default.
- W2037648717 hasConceptScore W2037648717C89423630 @default.
- W2037648717 hasConceptScore W2037648717C90924648 @default.
- W2037648717 hasConceptScore W2037648717C94665300 @default.
- W2037648717 hasIssue "2" @default.
- W2037648717 hasLocation W20376487171 @default.
- W2037648717 hasLocation W20376487172 @default.
- W2037648717 hasOpenAccess W2037648717 @default.
- W2037648717 hasPrimaryLocation W20376487171 @default.
- W2037648717 hasRelatedWork W1964637627 @default.
- W2037648717 hasRelatedWork W2000128505 @default.
- W2037648717 hasRelatedWork W2053631526 @default.
- W2037648717 hasRelatedWork W2130569918 @default.
- W2037648717 hasRelatedWork W2160020555 @default.
- W2037648717 hasRelatedWork W2171828589 @default.
- W2037648717 hasRelatedWork W2389079257 @default.
- W2037648717 hasRelatedWork W2419195486 @default.
- W2037648717 hasRelatedWork W25551450 @default.
- W2037648717 hasRelatedWork W4312640331 @default.
- W2037648717 hasVolume "52" @default.
- W2037648717 isParatext "false" @default.
- W2037648717 isRetracted "false" @default.
- W2037648717 magId "2037648717" @default.
- W2037648717 workType "article" @default.