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• W2037685690 abstract "An activity in human cell extracts is described that repairs DNA with loops of five or more unpaired bases. Repair is strand-specific and is directed by a nick located 5′ or 3′ to the loop. This repair is observed in a colorectal cancer cell line that is devoid of a wild-type hMLH1 gene and is deficient in repair of mismatches. However, a cell line with deletions in both hMSH2 alleles is deficient in repair of both loops and mismatches. Defects in loop repair may be relevant to the repetitive-sequence instability observed in cancers and other hereditary diseases." @default.
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• W2037685690 date "1994-11-04" @default.
• W2037685690 modified "2023-09-27" @default.
• W2037685690 title "DNA Loop Repair by Human Cell Extracts" @default.
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• W2037685690 doi "https://doi.org/10.1126/science.7973637" @default.
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