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- W2037695051 abstract "Type 2 diabetes is the most prevalent form of diabetes mellitus worldwide and associated diabetic nephropathy is the most common cause of end-stage renal disease in the USA. Lowering blood pressure and controlling glucose slows the progression to end-stage renal disease or death. Although angiotensin-converting-enzyme inhibitors reduce proteinuria, their effects to slow progression to end-stage renal disease have not been clearly demonstrated in type 2 diabetic nephropathy. Recent clinical trials with angiotensin AT(1) receptor antagonists demonstrate that they reduce proteinuria, stabilize renal function and slow the progression of nephropathy to end-stage renal disease in patients with type 2 diabetes. These are significant benefits beyond those associated with conventional therapy and blood pressure control." @default.
- W2037695051 created "2016-06-24" @default.
- W2037695051 creator A5037884146 @default.
- W2037695051 date "2002-04-01" @default.
- W2037695051 modified "2023-09-27" @default.
- W2037695051 title "Treatment of type 2 diabetic nephropathy by blockade of the renin–angiotensin system: a comparison of angiotensin-converting-enzyme inhibitors and angiotensin receptor antagonists" @default.
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- W2037695051 doi "https://doi.org/10.1016/s1471-4892(02)00141-8" @default.
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