FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037697005> ?p ?o ?g. }

• W2037697005 abstract "Tetracycline hydrochloride (TC), 30-70 mg/kg infused intravenously in dogs in the course of a few minutes, reduced clearance of inulin (Cin) and p-aminohippuric acid (CPAH) on an average to less than 5% of control. In spite of increased intrarenal pressure (approximately 50 mm Hg), electromagnetically recorded renal blood flow was preserved, indicating that the reduction of Cin and CPAH resulted from tubular obstruction, not renal vasoconstriction. The metabolic rate of the cortex and outer medulla fell to 69% of control after TC, as measured by the heat accumulation rate. Further reduction to basal metabolic level (30% of control) was reversibly produced by elevating ureteral pressure, suggesting that the high metabolic rate was caused by continued active reabsorption of sodium chloride at about half the control rate. Thus Cin greatly underestimated glomerular filtration rate in the TC-damaged kidney. From these results and the observation of TC-containing casts in the medullary tubules, we conclude that TC caused tubular obstruction and that leakage of inulin and PAH from the tubules occurred mainly distally to the major sodium-reabsorbing tubular segments." @default.
• W2037697005 created "2016-06-24" @default.
• W2037697005 creator A5059532036 @default.
• W2037697005 creator A5066706316 @default.
• W2037697005 creator A5074818799 @default.
• W2037697005 creator A5088961957 @default.
• W2037697005 date "1975-01-01" @default.
• W2037697005 modified "2023-10-18" @default.
• W2037697005 title "Mechanisms in Acute Oliguric Renal Failure Induced by Tetracydine Infusion" @default.
• W2037697005 cites W1899174309 @default.
• W2037697005 cites W1963963419 @default.
• W2037697005 cites W1965591807 @default.
• W2037697005 cites W1977720115 @default.
• W2037697005 cites W1977964839 @default.
• W2037697005 cites W1981975413 @default.
• W2037697005 cites W1983369324 @default.
• W2037697005 cites W2016670587 @default.
• W2037697005 cites W2017541277 @default.
• W2037697005 cites W2020228042 @default.
• W2037697005 cites W2030741743 @default.
• W2037697005 cites W2034287996 @default.
• W2037697005 cites W2036777710 @default.
• W2037697005 cites W2038481143 @default.
• W2037697005 cites W2067417881 @default.
• W2037697005 cites W2136043432 @default.
• W2037697005 cites W2339871742 @default.
• W2037697005 cites W2403669499 @default.
• W2037697005 cites W2403887122 @default.
• W2037697005 cites W2413327394 @default.
• W2037697005 cites W2421623069 @default.
• W2037697005 cites W2428614507 @default.
• W2037697005 cites W2471905569 @default.
• W2037697005 doi "https://doi.org/10.1080/00365517509095789" @default.
• W2037697005 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1209157" @default.
• W2037697005 hasPublicationYear "1975" @default.
• W2037697005 type Work @default.
• W2037697005 sameAs 2037697005 @default.
• W2037697005 citedByCount "2" @default.
• W2037697005 crossrefType "journal-article" @default.
• W2037697005 hasAuthorship W2037697005A5059532036 @default.
• W2037697005 hasAuthorship W2037697005A5066706316 @default.
• W2037697005 hasAuthorship W2037697005A5074818799 @default.
• W2037697005 hasAuthorship W2037697005A5088961957 @default.
• W2037697005 hasConcept C119584498 @default.
• W2037697005 hasConcept C126322002 @default.
• W2037697005 hasConcept C134018914 @default.
• W2037697005 hasConcept C142225936 @default.
• W2037697005 hasConcept C159641895 @default.
• W2037697005 hasConcept C161457703 @default.
• W2037697005 hasConcept C178790620 @default.
• W2037697005 hasConcept C185592680 @default.
• W2037697005 hasConcept C2776844834 @default.
• W2037697005 hasConcept C2776982352 @default.
• W2037697005 hasConcept C2778437025 @default.
• W2037697005 hasConcept C2779742124 @default.
• W2037697005 hasConcept C2780091579 @default.
• W2037697005 hasConcept C2780512574 @default.
• W2037697005 hasConcept C2781231759 @default.
• W2037697005 hasConcept C537181965 @default.
• W2037697005 hasConcept C55493867 @default.
• W2037697005 hasConcept C56906281 @default.
• W2037697005 hasConcept C57476199 @default.
• W2037697005 hasConcept C71924100 @default.
• W2037697005 hasConceptScore W2037697005C119584498 @default.
• W2037697005 hasConceptScore W2037697005C126322002 @default.
• W2037697005 hasConceptScore W2037697005C134018914 @default.
• W2037697005 hasConceptScore W2037697005C142225936 @default.
• W2037697005 hasConceptScore W2037697005C159641895 @default.
• W2037697005 hasConceptScore W2037697005C161457703 @default.
• W2037697005 hasConceptScore W2037697005C178790620 @default.
• W2037697005 hasConceptScore W2037697005C185592680 @default.
• W2037697005 hasConceptScore W2037697005C2776844834 @default.
• W2037697005 hasConceptScore W2037697005C2776982352 @default.
• W2037697005 hasConceptScore W2037697005C2778437025 @default.
• W2037697005 hasConceptScore W2037697005C2779742124 @default.
• W2037697005 hasConceptScore W2037697005C2780091579 @default.
• W2037697005 hasConceptScore W2037697005C2780512574 @default.
• W2037697005 hasConceptScore W2037697005C2781231759 @default.
• W2037697005 hasConceptScore W2037697005C537181965 @default.
• W2037697005 hasConceptScore W2037697005C55493867 @default.
• W2037697005 hasConceptScore W2037697005C56906281 @default.
• W2037697005 hasConceptScore W2037697005C57476199 @default.
• W2037697005 hasConceptScore W2037697005C71924100 @default.
• W2037697005 hasLocation W20376970051 @default.
• W2037697005 hasLocation W20376970052 @default.
• W2037697005 hasOpenAccess W2037697005 @default.
• W2037697005 hasPrimaryLocation W20376970051 @default.
• W2037697005 hasRelatedWork W169970500 @default.
• W2037697005 hasRelatedWork W1810450547 @default.
• W2037697005 hasRelatedWork W1969030939 @default.
• W2037697005 hasRelatedWork W2052014291 @default.
• W2037697005 hasRelatedWork W2069986440 @default.
• W2037697005 hasRelatedWork W2076237833 @default.
• W2037697005 hasRelatedWork W2165059883 @default.
• W2037697005 hasRelatedWork W2388619682 @default.
• W2037697005 hasRelatedWork W2460713251 @default.
• W2037697005 hasRelatedWork W39985546 @default.
• W2037697005 isParatext "false" @default.
• W2037697005 isRetracted "false" @default.
• W2037697005 magId "2037697005" @default.

• next