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- W2037702967 abstract "<i>Background:</i> Morbidity and mortality due to anastomotic complications in gastrointestinal surgery remain important problems. The tissue adhesive N-butyl-2-cyanoacrylate (NB2CA) is used in many fields of surgery. This study was designed to assess the effects of NB2CA on high-level jejunojejunostomy. <i>Materials and Methods:</i> Forty male albino Wistar rats were divided into 4 groups of 10 each. The groups were treated as follows: group 1 underwent only a jejunojejunostomy, group 2 underwent jejunojejunostomy followed by NB2CA application around the anastomosis, group 3 underwent jejunojejunostomy after a 60-min ischemia and a 60-min reperfusion, and group 4 underwent jejunojejunostomy after a 60-min ischemia and a 60-min reperfusion followed by NB2CA application around the anastomosis. At postoperative day 7, the subjects in all groups were sacrificed. Intra-abdominal adhesions, anastomotic complications and anastomotic burst pressures (ABP) were recorded. <i>Results:</i> The analysis of all the groups for adhesion scores and ABP showed statistical significance (p < 0.001). <i>Conclusions:</i> The use of NB2CA had positive effects in terms of increasing ABP both with and without the initial ischemia- reperfusion insult. However, it had the adverse effect of significantly increasing the number of intra-abdominal adhesions." @default.
- W2037702967 created "2016-06-24" @default.
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- W2037702967 date "2009-11-12" @default.
- W2037702967 modified "2023-10-16" @default.
- W2037702967 title "Effects of N-Butyl-2-Cyanoacrylate on High-Level Jejunojejunostomy" @default.
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- W2037702967 doi "https://doi.org/10.1159/000257969" @default.
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