Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037737270> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2037737270 endingPage "7836" @default.
- W2037737270 startingPage "7832" @default.
- W2037737270 abstract "The HLA-A2 antigen-specific monoclonal antibody BB7.2 and complement were used to immunoselect mutants from an ethyl methanesulfonate-mutagenized human B lymphoid cell line, T5-1. Surviving colonies were screened by radioimmune binding with BB7.2 and with a monospecific HLA-A2 alloantiserum, Stewart, and HLA antigens of selected clones were immunoprecipitated and studied by isoelectric focusing. Several classes of mutants could be distinguished: mutants that expressed no HLA-A2 heavy chain; mutants that expressed an HLA-A2 heavy chain that was unable to associate with beta 2-microglobulin (beta 2m) and was not expressed at the cell surface; mutants with reduced HLA-A2 heavy chain-beta 2m association and cell surface expression of HLA-A2 dimer with or without heavy chain charge alterations; mutants with normal HLA-A2 heavy chain-beta 2m association and normal quantitative cell surface HLA-A2 expression but with HLA-A2 heavy chain charge alterations; and mutants with as yet incompletely defined lesions. Mutants with altered cell surface HLA antigens were not found in previous selections with alloantisera and should be useful for epitope mapping and structure-function studies of HLA molecules." @default.
- W2037737270 created "2016-06-24" @default.
- W2037737270 creator A5038803630 @default.
- W2037737270 creator A5040129865 @default.
- W2037737270 creator A5065611635 @default.
- W2037737270 creator A5075092692 @default.
- W2037737270 creator A5081806648 @default.
- W2037737270 date "1982-12-01" @default.
- W2037737270 modified "2023-09-27" @default.
- W2037737270 title "HLA antigen structural gene mutants selected with an allospecific monoclonal antibody." @default.
- W2037737270 cites W1485388309 @default.
- W2037737270 cites W1506397040 @default.
- W2037737270 cites W1544239845 @default.
- W2037737270 cites W1547352154 @default.
- W2037737270 cites W1550374675 @default.
- W2037737270 cites W1554347661 @default.
- W2037737270 cites W1588885776 @default.
- W2037737270 cites W1969149509 @default.
- W2037737270 cites W1986435148 @default.
- W2037737270 cites W1996739074 @default.
- W2037737270 cites W2008774884 @default.
- W2037737270 cites W2022472700 @default.
- W2037737270 cites W2026970642 @default.
- W2037737270 cites W2027972796 @default.
- W2037737270 cites W2031656934 @default.
- W2037737270 cites W2038715182 @default.
- W2037737270 cites W2040141085 @default.
- W2037737270 cites W2058653058 @default.
- W2037737270 cites W2069703570 @default.
- W2037737270 cites W2073205055 @default.
- W2037737270 cites W2086334254 @default.
- W2037737270 cites W2090230058 @default.
- W2037737270 cites W2090541956 @default.
- W2037737270 cites W2092829393 @default.
- W2037737270 cites W2103885409 @default.
- W2037737270 cites W2113746427 @default.
- W2037737270 doi "https://doi.org/10.1073/pnas.79.24.7832" @default.
- W2037737270 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/347443" @default.
- W2037737270 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6961455" @default.
- W2037737270 hasPublicationYear "1982" @default.
- W2037737270 type Work @default.
- W2037737270 sameAs 2037737270 @default.
- W2037737270 citedByCount "30" @default.
- W2037737270 crossrefType "journal-article" @default.
- W2037737270 hasAuthorship W2037737270A5038803630 @default.
- W2037737270 hasAuthorship W2037737270A5040129865 @default.
- W2037737270 hasAuthorship W2037737270A5065611635 @default.
- W2037737270 hasAuthorship W2037737270A5075092692 @default.
- W2037737270 hasAuthorship W2037737270A5081806648 @default.
- W2037737270 hasBestOaLocation W20377372701 @default.
- W2037737270 hasConcept C104317684 @default.
- W2037737270 hasConcept C143065580 @default.
- W2037737270 hasConcept C147483822 @default.
- W2037737270 hasConcept C153911025 @default.
- W2037737270 hasConcept C159654299 @default.
- W2037737270 hasConcept C188280979 @default.
- W2037737270 hasConcept C195616568 @default.
- W2037737270 hasConcept C542903549 @default.
- W2037737270 hasConcept C54355233 @default.
- W2037737270 hasConcept C86803240 @default.
- W2037737270 hasConceptScore W2037737270C104317684 @default.
- W2037737270 hasConceptScore W2037737270C143065580 @default.
- W2037737270 hasConceptScore W2037737270C147483822 @default.
- W2037737270 hasConceptScore W2037737270C153911025 @default.
- W2037737270 hasConceptScore W2037737270C159654299 @default.
- W2037737270 hasConceptScore W2037737270C188280979 @default.
- W2037737270 hasConceptScore W2037737270C195616568 @default.
- W2037737270 hasConceptScore W2037737270C542903549 @default.
- W2037737270 hasConceptScore W2037737270C54355233 @default.
- W2037737270 hasConceptScore W2037737270C86803240 @default.
- W2037737270 hasIssue "24" @default.
- W2037737270 hasLocation W20377372701 @default.
- W2037737270 hasLocation W20377372702 @default.
- W2037737270 hasLocation W20377372703 @default.
- W2037737270 hasLocation W20377372704 @default.
- W2037737270 hasOpenAccess W2037737270 @default.
- W2037737270 hasPrimaryLocation W20377372701 @default.
- W2037737270 hasRelatedWork W1604248381 @default.
- W2037737270 hasRelatedWork W1973692620 @default.
- W2037737270 hasRelatedWork W1997512836 @default.
- W2037737270 hasRelatedWork W1999614011 @default.
- W2037737270 hasRelatedWork W2001280522 @default.
- W2037737270 hasRelatedWork W2041069158 @default.
- W2037737270 hasRelatedWork W2090054751 @default.
- W2037737270 hasRelatedWork W2092720945 @default.
- W2037737270 hasRelatedWork W2162389703 @default.
- W2037737270 hasRelatedWork W2400620861 @default.
- W2037737270 hasVolume "79" @default.
- W2037737270 isParatext "false" @default.
- W2037737270 isRetracted "false" @default.
- W2037737270 magId "2037737270" @default.
- W2037737270 workType "article" @default.