FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037744856> ?p ?o ?g. }

• W2037744856 endingPage "84" @default.
• W2037744856 startingPage "77" @default.
• W2037744856 abstract "A simple high-performance liquid chromatographic method for the measurement of diazepam (DZP) and its major metabolites, N-desmethyldiazepam (DMDZP), temazepam (TZP) and oxazepam (OZP) in urine was developed. Preliminary studies of DZP metabolism were also undertaken in four healthy volunteers after administration of a single oral dose (4 mg) of DZP. The assay allowed the simultaneous determination of all analytes in 1 ml of urine and the detection limit was 2 ng/ml with a signal-to-noise ratio of 3. None of 22 drugs and 17 metabolites, except for mianserin, maprotiline and imipramine N-oxide, interfered with the detection of DZP metabolites. Recoveries of the analytes and the internal standard (prazepam) were >82%. Intra- and inter-assay coefficients of variation for all analytes were <5.5 and 4.1.%, respectively. The mean (±S.D.) cumulative urinary excretions of DMDZP, TZP and OZP over 96 h after a single oral administration of DZP were 3.9±0.4, 6.6±1.4 and 2.8±0.6% of the dose, respectively. The urinary excretion of DZP was under the detection limit." @default.
• W2037744856 created "2016-06-24" @default.
• W2037744856 creator A5003704839 @default.
• W2037744856 creator A5013823416 @default.
• W2037744856 creator A5020349194 @default.
• W2037744856 creator A5020888659 @default.
• W2037744856 creator A5031345854 @default.
• W2037744856 creator A5062376392 @default.
• W2037744856 date "1995-06-01" @default.
• W2037744856 modified "2023-10-16" @default.
• W2037744856 title "Development and preliminary application of high-performance liquid chromatographic assay of urinary metabolites of diazepam in humans" @default.
• W2037744856 cites W1970092147 @default.
• W2037744856 cites W1970766892 @default.
• W2037744856 cites W1971736210 @default.
• W2037744856 cites W1976138388 @default.
• W2037744856 cites W1977570405 @default.
• W2037744856 cites W1986388157 @default.
• W2037744856 cites W2007801282 @default.
• W2037744856 cites W2010669389 @default.
• W2037744856 cites W2011356146 @default.
• W2037744856 cites W2012515901 @default.
• W2037744856 cites W2028599478 @default.
• W2037744856 cites W2033564508 @default.
• W2037744856 cites W2074774987 @default.
• W2037744856 cites W2092804460 @default.
• W2037744856 cites W2119248593 @default.
• W2037744856 cites W3214709855 @default.
• W2037744856 doi "https://doi.org/10.1016/0378-4347(95)00050-s" @default.
• W2037744856 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7550984" @default.
• W2037744856 hasPublicationYear "1995" @default.
• W2037744856 type Work @default.
• W2037744856 sameAs 2037744856 @default.
• W2037744856 citedByCount "27" @default.
• W2037744856 countsByYear W20377448562012 @default.
• W2037744856 countsByYear W20377448562014 @default.
• W2037744856 countsByYear W20377448562017 @default.
• W2037744856 countsByYear W20377448562018 @default.
• W2037744856 countsByYear W20377448562022 @default.
• W2037744856 crossrefType "journal-article" @default.
• W2037744856 hasAuthorship W2037744856A5003704839 @default.
• W2037744856 hasAuthorship W2037744856A5013823416 @default.
• W2037744856 hasAuthorship W2037744856A5020349194 @default.
• W2037744856 hasAuthorship W2037744856A5020888659 @default.
• W2037744856 hasAuthorship W2037744856A5031345854 @default.
• W2037744856 hasAuthorship W2037744856A5062376392 @default.
• W2037744856 hasConcept C10390740 @default.
• W2037744856 hasConcept C119128265 @default.
• W2037744856 hasConcept C142724271 @default.
• W2037744856 hasConcept C170493617 @default.
• W2037744856 hasConcept C185592680 @default.
• W2037744856 hasConcept C204787440 @default.
• W2037744856 hasConcept C2776175493 @default.
• W2037744856 hasConcept C2776615572 @default.
• W2037744856 hasConcept C2777207853 @default.
• W2037744856 hasConcept C2777477808 @default.
• W2037744856 hasConcept C2778173252 @default.
• W2037744856 hasConcept C2779145073 @default.
• W2037744856 hasConcept C2780026642 @default.
• W2037744856 hasConcept C2780756443 @default.
• W2037744856 hasConcept C2781006864 @default.
• W2037744856 hasConcept C43617362 @default.
• W2037744856 hasConcept C55493867 @default.
• W2037744856 hasConcept C71924100 @default.
• W2037744856 hasConcept C98274493 @default.
• W2037744856 hasConceptScore W2037744856C10390740 @default.
• W2037744856 hasConceptScore W2037744856C119128265 @default.
• W2037744856 hasConceptScore W2037744856C142724271 @default.
• W2037744856 hasConceptScore W2037744856C170493617 @default.
• W2037744856 hasConceptScore W2037744856C185592680 @default.
• W2037744856 hasConceptScore W2037744856C204787440 @default.
• W2037744856 hasConceptScore W2037744856C2776175493 @default.
• W2037744856 hasConceptScore W2037744856C2776615572 @default.
• W2037744856 hasConceptScore W2037744856C2777207853 @default.
• W2037744856 hasConceptScore W2037744856C2777477808 @default.
• W2037744856 hasConceptScore W2037744856C2778173252 @default.
• W2037744856 hasConceptScore W2037744856C2779145073 @default.
• W2037744856 hasConceptScore W2037744856C2780026642 @default.
• W2037744856 hasConceptScore W2037744856C2780756443 @default.
• W2037744856 hasConceptScore W2037744856C2781006864 @default.
• W2037744856 hasConceptScore W2037744856C43617362 @default.
• W2037744856 hasConceptScore W2037744856C55493867 @default.
• W2037744856 hasConceptScore W2037744856C71924100 @default.
• W2037744856 hasConceptScore W2037744856C98274493 @default.
• W2037744856 hasIssue "1" @default.
• W2037744856 hasLocation W20377448561 @default.
• W2037744856 hasLocation W20377448562 @default.
• W2037744856 hasOpenAccess W2037744856 @default.
• W2037744856 hasPrimaryLocation W20377448561 @default.
• W2037744856 hasRelatedWork W1447129908 @default.
• W2037744856 hasRelatedWork W1587379072 @default.
• W2037744856 hasRelatedWork W1969814763 @default.
• W2037744856 hasRelatedWork W1975683673 @default.
• W2037744856 hasRelatedWork W2006420435 @default.
• W2037744856 hasRelatedWork W2006715918 @default.
• W2037744856 hasRelatedWork W2028754989 @default.
• W2037744856 hasRelatedWork W2312907147 @default.
• W2037744856 hasRelatedWork W4214835118 @default.
• W2037744856 hasRelatedWork W4245704349 @default.

• next