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- W2037785033 abstract "We report ocular findings in a patient with Darier disease. In particular, we discuss the in vivo confocal images.A retrospective noninterventional case report.Confocal microscopy revealed collections of intercellular material, separating the cells of the patient's basal corneal epithelium. Discrete foci of this material were scattered throughout the central corneal basal epithelium in both eyes. These deposits had a similar reflectance as corneal nerves, were 3-5-microm thick, and of note in places conformed to the cell borders.The findings of abnormal intercellular collections at the basal epithelial layer of the cornea correlate with the previously reported histological findings. They are consistent with the abnormal keratocyte-to-keratocyte adhesions that are described both in the skin and cornea of Darier disease. The abnormalities we describe occurred in the absence of other ocular signs of Darier disease. These findings on confocal microscopy may help with the diagnosis and monitoring of disease progression." @default.
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- W2037785033 date "2010-07-01" @default.
- W2037785033 modified "2023-09-26" @default.
- W2037785033 title "Corneal Confocal Microscopy in Darier Disease" @default.
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- W2037785033 doi "https://doi.org/10.1097/ico.0b013e3181c58f1b" @default.
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