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• W2037793313 startingPage "65" @default.
• W2037793313 abstract "In many patients with coronary artery disease, a low level of high-density lipoprotein cholesterol (HDL-C), rather than substantially elevated lowdensity lipoprotein cholesterol (LDL-C), is often the predominant lipid abnormality. Although the National Cholesterol Education Program treatment guidelines include HDL-C concentration as a major risk factor for primary prevention, the guidelines' emphasis on LDL-C as the primary target of therapy may cause uncertainty as to whether risk reduction strategies should focus on lowering LDL-C or raising HDL-C in high-risk patients with low HDL-C. Recent clinical trial evidence and epidemiologic data suggest that HDL-C should play a more important role in risk assessment, and that the definition of low HDL-C may need adjustment from the current National Cholesterol Education Program definition of <35 mg/dL to perhaps <40 mg/dL in men and <45 mg/dL in women. Patients with low HDL-C should receive aggressive risk factor modification, and more emphasis on increasing HDL-C may be warranted in addition to lowering LDL-C." @default.
• W2037793313 created "2016-06-24" @default.
• W2037793313 creator A5006242164 @default.
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• W2037793313 date "2001-04-01" @default.
• W2037793313 modified "2023-09-25" @default.
• W2037793313 title "The Evolving Role of High-Density Lipoprotein in Reducing Cardiovascular Risk" @default.
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• W2037793313 doi "https://doi.org/10.1111/j.1520-037x.2001.00556.x" @default.
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