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- W2037804925 abstract "We have mapped the sites of ischemia/reperfusion-induced phosphorylation of cytochrome c oxidase (CcO) subunits in rabbit hearts by using a combination of Blue Native gel/Tricine gel electrophoresis and nano-LC-MS/MS approaches. We used precursor ion scanning combined with neutral loss scanning and found that mature CcO subunit I was phosphorylated at tandem Ser115/Ser116 positions, subunit IVi1 at Thr52 and subunit Vb at Ser40. These sites are highly conserved in mammalian species. Molecular modeling suggests that phosphorylation sites of subunit I face the inter membrane space while those of subunits IVi1 and Vb face the matrix side." @default.
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- W2037804925 date "2007-02-28" @default.
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- W2037804925 title "Site specific phosphorylation of cytochrome<i>c</i>oxidase subunits I, IVi1 and Vb in rabbit hearts subjected to ischemia/reperfusion" @default.
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- W2037804925 doi "https://doi.org/10.1016/j.febslet.2007.02.042" @default.
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