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• W2037861644 startingPage "334" @default.
• W2037861644 abstract "We have employed mannose-modified gold nanodots (Man-Au NDs) as a luminescence sensor for the detection of the thyroid-cancer marker thyroglobulin (Tg) in homogeneous solutions. The luminescent Man-Au NDs are prepared through the reaction of 2.9 nm-diameter gold nanoparticles (Au NPs) with 11-mercapto-3,6,9-trioxaundecyl-alpha-D-mannopyranoside (Man-RSH) under the irradiation of a light-emitting diode (LED). We have found that the irradiation enhances the quantum yield (approximately 11%), alters the emission wavelength and lifetimes, and shortens the preparation time. A luminescence assay has been developed for Tg based on the competition between Tg and Man-Au NDs for the interaction with the concanavalin A (Con A). Because luminescence quenching of the Man-Au NDs by Con A is inhibited by Tg selectivity, we have obtained a highly sensitive and selective assay for Tg." @default.
• W2037861644 created "2016-06-24" @default.
• W2037861644 creator A5000010847 @default.
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• W2037861644 creator A5078085712 @default.
• W2037861644 date "2010-01-28" @default.
• W2037861644 modified "2023-10-18" @default.
• W2037861644 title "Photoassisted Synthesis of Luminescent Mannose-Au Nanodots for the Detection of Thyroglobulin in Serum" @default.
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• W2037861644 doi "https://doi.org/10.1002/asia.200900346" @default.
• W2037861644 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20063339" @default.
• W2037861644 hasPublicationYear "2010" @default.
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