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- W2037893670 abstract "Adult stem cells are found in various tissues and organs and have potential to differentiate into different cell lineages, including bone, cartilage, fat, tendon, muscle, epithelial cells of the skin and gastrointestinal tract, etc. Here, we report that the expended and purified bone marrow MSCs might take on phenotypes and characteristics of vascular endothelial cells or epidermal cells after cultured and induced with different lineage-specific culture conditions in vitro. Also, in vivo grafting experiments confirmed that those labeled MSCs could get the phenotypes of vascular endothelial cells in granulation tissue and sebaceous duct cells and epidermal cells in regenerated skin, which imply that these grafted MSCs might have transdifferentiated into vascular endothelial cells and sebaceous duct cells and epidermal cells. Our results indicate that locally delivered bone marrow MSCs may generate de novo intact skin and get perfect skin regeneration after full thickness injury." @default.
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- W2037893670 date "2004-03-01" @default.
- W2037893670 modified "2023-09-25" @default.
- W2037893670 title "085 Bone Marrow Mesenchymal Stem Cells as a Potential Source to Repair the Injury Skin" @default.
- W2037893670 doi "https://doi.org/10.1111/j.1067-1927.2004.0abstractcd.x" @default.
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