Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037955607> ?p ?o ?g. }
- W2037955607 endingPage "280" @default.
- W2037955607 startingPage "272" @default.
- W2037955607 abstract "Human cytomegalovirus (HCMV)-specific antibody responses in HIV-1 infected individuals either with or without HCMV end-organ disease were examined to determine the whether development of HCMV disease was associated with a particular deficit in the antibody response. Antiwhole HCMV, anti-glycoprotein B (gB), and neutralizing antibody levels were higher in HIV-1 infected individuals than in healthy immunocompetent subjects, particularly in patients with AIDS either with or without HCMV-associated disease. Irrespective of location and spread of HCMV disease, patients who had received anti-HCMV therapy prior to sampling exhibited significantly higher anti-gB and neutralizing antibody titers than those who remained untreated. Likewise, patients with HCMV disease who were antigenemic or viremic had significantly lower anti-gB and neutralizing antibody titers than those who tested negative in either assay. Patients with untreated HCMV disease had significantly lower antibody titers than AIDS patients without disease. Analysis of the IgG subclass antibody responses to gB revealed no significant differences among HIV-1 infected individuals. These results suggest that levels of detectable anti-gB and HCMV neutralizing antibodies are inversely related to systemic viral load. Thus, antibodies with such specificities may be relevant in preventing the establishment of HCMV-associated disease or in modulating its progression." @default.
- W2037955607 created "2016-06-24" @default.
- W2037955607 creator A5007588019 @default.
- W2037955607 creator A5008717419 @default.
- W2037955607 creator A5012932760 @default.
- W2037955607 creator A5020258093 @default.
- W2037955607 creator A5033161933 @default.
- W2037955607 creator A5041136846 @default.
- W2037955607 creator A5048667108 @default.
- W2037955607 creator A5057536435 @default.
- W2037955607 creator A5060172614 @default.
- W2037955607 creator A5089590633 @default.
- W2037955607 date "1998-08-01" @default.
- W2037955607 modified "2023-09-24" @default.
- W2037955607 title "Antibody response to human cytomegalovirus (HCMV) glycoprotein B (gB) in AIDS patients with HCMV end-organ disease" @default.
- W2037955607 cites W1485532299 @default.
- W2037955607 cites W1619193367 @default.
- W2037955607 cites W1811774078 @default.
- W2037955607 cites W1826181374 @default.
- W2037955607 cites W1948248797 @default.
- W2037955607 cites W1967840486 @default.
- W2037955607 cites W1968772953 @default.
- W2037955607 cites W1973361064 @default.
- W2037955607 cites W1974303748 @default.
- W2037955607 cites W1976427045 @default.
- W2037955607 cites W1988863963 @default.
- W2037955607 cites W2005679373 @default.
- W2037955607 cites W2024092184 @default.
- W2037955607 cites W2028553357 @default.
- W2037955607 cites W2036344707 @default.
- W2037955607 cites W2044112196 @default.
- W2037955607 cites W2068787010 @default.
- W2037955607 cites W2069779373 @default.
- W2037955607 cites W2091055845 @default.
- W2037955607 cites W2091443605 @default.
- W2037955607 cites W2091978710 @default.
- W2037955607 cites W2103159012 @default.
- W2037955607 cites W2110515405 @default.
- W2037955607 cites W2125027704 @default.
- W2037955607 cites W2131018431 @default.
- W2037955607 cites W2132678929 @default.
- W2037955607 cites W2133233264 @default.
- W2037955607 cites W2139633463 @default.
- W2037955607 cites W2143261542 @default.
- W2037955607 cites W2148503974 @default.
- W2037955607 cites W2151908623 @default.
- W2037955607 cites W2160195746 @default.
- W2037955607 cites W2161732543 @default.
- W2037955607 cites W2319153630 @default.
- W2037955607 cites W2319346699 @default.
- W2037955607 cites W97674068 @default.
- W2037955607 doi "https://doi.org/10.1002/(sici)1096-9071(199808)55:4<272::aid-jmv4>3.0.co;2-y" @default.
- W2037955607 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9661835" @default.
- W2037955607 hasPublicationYear "1998" @default.
- W2037955607 type Work @default.
- W2037955607 sameAs 2037955607 @default.
- W2037955607 citedByCount "14" @default.
- W2037955607 countsByYear W20379556072016 @default.
- W2037955607 crossrefType "journal-article" @default.
- W2037955607 hasAuthorship W2037955607A5007588019 @default.
- W2037955607 hasAuthorship W2037955607A5008717419 @default.
- W2037955607 hasAuthorship W2037955607A5012932760 @default.
- W2037955607 hasAuthorship W2037955607A5020258093 @default.
- W2037955607 hasAuthorship W2037955607A5033161933 @default.
- W2037955607 hasAuthorship W2037955607A5041136846 @default.
- W2037955607 hasAuthorship W2037955607A5048667108 @default.
- W2037955607 hasAuthorship W2037955607A5057536435 @default.
- W2037955607 hasAuthorship W2037955607A5060172614 @default.
- W2037955607 hasAuthorship W2037955607A5089590633 @default.
- W2037955607 hasConcept C142462285 @default.
- W2037955607 hasConcept C159047783 @default.
- W2037955607 hasConcept C159654299 @default.
- W2037955607 hasConcept C203014093 @default.
- W2037955607 hasConcept C2522874641 @default.
- W2037955607 hasConcept C2776409557 @default.
- W2037955607 hasConcept C2777662283 @default.
- W2037955607 hasConcept C2777732132 @default.
- W2037955607 hasConcept C2779261636 @default.
- W2037955607 hasConcept C2779820661 @default.
- W2037955607 hasConcept C2780727368 @default.
- W2037955607 hasConcept C32611913 @default.
- W2037955607 hasConcept C71924100 @default.
- W2037955607 hasConceptScore W2037955607C142462285 @default.
- W2037955607 hasConceptScore W2037955607C159047783 @default.
- W2037955607 hasConceptScore W2037955607C159654299 @default.
- W2037955607 hasConceptScore W2037955607C203014093 @default.
- W2037955607 hasConceptScore W2037955607C2522874641 @default.
- W2037955607 hasConceptScore W2037955607C2776409557 @default.
- W2037955607 hasConceptScore W2037955607C2777662283 @default.
- W2037955607 hasConceptScore W2037955607C2777732132 @default.
- W2037955607 hasConceptScore W2037955607C2779261636 @default.
- W2037955607 hasConceptScore W2037955607C2779820661 @default.
- W2037955607 hasConceptScore W2037955607C2780727368 @default.
- W2037955607 hasConceptScore W2037955607C32611913 @default.
- W2037955607 hasConceptScore W2037955607C71924100 @default.
- W2037955607 hasIssue "4" @default.
- W2037955607 hasLocation W20379556071 @default.
- W2037955607 hasLocation W20379556072 @default.