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- W2037956735 endingPage "268" @default.
- W2037956735 startingPage "257" @default.
- W2037956735 abstract "It has been suggested that intraoperative neuraxial (spinal, epidural) anesthesia may decrease postoperative cognitive dysfunction when compared with general anesthesia, but the issue remains controversial. We systematically reviewed the data from published studies to determine the effect of intraoperative neuraxial anesthesia versus general anesthesia on postoperative cognitive dysfunction and delirium.Studies were identified by searching the PubMed database of the National Library of Medicine (1966 to 2003) for terms related to cognitive dysfunction after surgery. Inclusion criteria were a comparison of intraoperative neuraxial anesthesia versus general anesthesia, and the outcome of postoperative cognitive dysfunction. A total of 196 abstracts were identified, and 24 articles were analyzed. Each article was reviewed, and data were extracted from tables or text or extrapolated from figures as needed.Of the 24 trials obtained, 19 were randomized and 4 were observational (nonrandomized) trials (1 trial was a combination of randomized and observational data). The age of patients studied was typically greater than 60 years, and a wide range of neuropsychometric tests were used to evaluate cognitive function. The majority of trials (23/24 of all trials and 18/19 of randomized trials) did not demonstrate a benefit from neuraxial anesthesia in decreasing the incidence of postoperative cognitive dysfunction.The use of intraoperative neuraxial anesthesia does not appear to decrease the incidence of postoperative cognitive dysfunction when compared with general anesthesia. There are methodologic and study-design issues present in many studies, and further elucidation of the pathophysiology of postoperative cognitive dysfunction may provide a direction for future studies." @default.
- W2037956735 created "2016-06-24" @default.
- W2037956735 creator A5014979799 @default.
- W2037956735 creator A5062787116 @default.
- W2037956735 creator A5084387360 @default.
- W2037956735 creator A5089858947 @default.
- W2037956735 date "2004-06-01" @default.
- W2037956735 modified "2023-10-17" @default.
- W2037956735 title "Postoperative cognitive function as an outcome of regional anesthesia and analgesia" @default.
- W2037956735 cites W1758222107 @default.
- W2037956735 cites W1957197433 @default.
- W2037956735 cites W1966897254 @default.
- W2037956735 cites W1967212159 @default.
- W2037956735 cites W1967465506 @default.
- W2037956735 cites W1971820063 @default.
- W2037956735 cites W1972120750 @default.
- W2037956735 cites W1974831946 @default.
- W2037956735 cites W1976233956 @default.
- W2037956735 cites W1979637370 @default.
- W2037956735 cites W1983485985 @default.
- W2037956735 cites W1984949064 @default.
- W2037956735 cites W1988076368 @default.
- W2037956735 cites W1993225155 @default.
- W2037956735 cites W1993911593 @default.
- W2037956735 cites W1994035412 @default.
- W2037956735 cites W2002911641 @default.
- W2037956735 cites W2003138400 @default.
- W2037956735 cites W2008024504 @default.
- W2037956735 cites W2010285979 @default.
- W2037956735 cites W2015882634 @default.
- W2037956735 cites W2019005116 @default.
- W2037956735 cites W2019202486 @default.
- W2037956735 cites W2019629325 @default.
- W2037956735 cites W2021604439 @default.
- W2037956735 cites W2023251400 @default.
- W2037956735 cites W2024081973 @default.
- W2037956735 cites W2027396121 @default.
- W2037956735 cites W2027595176 @default.
- W2037956735 cites W2027988979 @default.
- W2037956735 cites W2028125985 @default.
- W2037956735 cites W2029677152 @default.
- W2037956735 cites W2032313326 @default.
- W2037956735 cites W2034773045 @default.
- W2037956735 cites W2037505626 @default.
- W2037956735 cites W2040329935 @default.
- W2037956735 cites W2047494429 @default.
- W2037956735 cites W2056357915 @default.
- W2037956735 cites W2056488135 @default.
- W2037956735 cites W2057472695 @default.
- W2037956735 cites W2058988280 @default.
- W2037956735 cites W2061880523 @default.
- W2037956735 cites W2063055024 @default.
- W2037956735 cites W2064590051 @default.
- W2037956735 cites W2064833264 @default.
- W2037956735 cites W2066159612 @default.
- W2037956735 cites W2069248151 @default.
- W2037956735 cites W2074378860 @default.
- W2037956735 cites W2074860531 @default.
- W2037956735 cites W2077328743 @default.
- W2037956735 cites W2081087260 @default.
- W2037956735 cites W2082138009 @default.
- W2037956735 cites W2082162853 @default.
- W2037956735 cites W2085515436 @default.
- W2037956735 cites W2086541726 @default.
- W2037956735 cites W2088577369 @default.
- W2037956735 cites W2089987094 @default.
- W2037956735 cites W2097142000 @default.
- W2037956735 cites W2104353128 @default.
- W2037956735 cites W2113389292 @default.
- W2037956735 cites W2120344067 @default.
- W2037956735 cites W2121457428 @default.
- W2037956735 cites W2127392537 @default.
- W2037956735 cites W2132852578 @default.
- W2037956735 cites W2140770928 @default.
- W2037956735 cites W2141885592 @default.
- W2037956735 cites W2142157411 @default.
- W2037956735 cites W2143050153 @default.
- W2037956735 cites W2145950876 @default.
- W2037956735 cites W2150841915 @default.
- W2037956735 cites W2154365828 @default.
- W2037956735 cites W2155233219 @default.
- W2037956735 cites W2157411708 @default.
- W2037956735 cites W2161900026 @default.
- W2037956735 cites W2161953596 @default.
- W2037956735 cites W2162055755 @default.
- W2037956735 cites W2163856468 @default.
- W2037956735 cites W2164748247 @default.
- W2037956735 cites W2168933629 @default.
- W2037956735 cites W2168962455 @default.
- W2037956735 cites W2170304509 @default.
- W2037956735 cites W2259875908 @default.
- W2037956735 cites W2329261975 @default.
- W2037956735 cites W2397240647 @default.
- W2037956735 cites W2400700506 @default.
- W2037956735 cites W2403807583 @default.
- W2037956735 cites W2413562758 @default.
- W2037956735 cites W2461742254 @default.
- W2037956735 cites W2764551176 @default.