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- W2037999758 abstract "Abstract Electroimmunodiffusion (electrophoresis in antibody-containing gel) was used to determine the α1-antitrypsin and α2-macroglobulin concentration of serum. The methodological error of the method, the influence of antigen and antibody concentration and the influence of non-specific antibodies were studied and discussed. The α1-antitrypsin and α2-macroglobulin contents were measured in the sera of 50 healthy, 20-year-old male blood donors and of 193 hospital patients. In healthy subjects the α2-macroglobulin values were much more dispersed than the α1-antitrypsin ones. None of the patients groups studied had normal concentrations of α1-antitrypsin whereas almost all of them had normal levels of α2-macroglobulin. This difference is further illustrated by a non-significant correlation between the two globulins. The pathological sera were also tested for their trypsin- and chymotrypsin-inhibiting capacities. A highly significant correlation was found between the α1-antitrypsin and the protease-inhibiting capacity." @default.
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- W2037999758 date "1971-01-01" @default.
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- W2037999758 title "The α1-antitrypsin and α2-macroglobulin content and the protease-inhibiting capacity of normal and pathological sera" @default.
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- W2037999758 doi "https://doi.org/10.1016/0009-8981(71)90382-2" @default.
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