FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038004015> ?p ?o ?g. }

• W2038004015 endingPage "901" @default.
• W2038004015 startingPage "892" @default.
• W2038004015 abstract "Objective Inhaled methoxyflurane (Penthrox, Medical Device International, Melbourne, Australia) has been used extensively in Australasia (Australia and New Zealand) to manage trauma-related pain. The aim is to evaluate the efficacy, safety, and outcome of Penthrox for colonoscopy. Design Prospective randomized study. Setting Three tertiary endoscopic centers. Patients Two hundred fifty-one patients were randomized to receive either Penthrox (n = 125, 70 men, 51.4 ± 1.1 years old) or intravenous midazolam and fentanyl (M&F; n = 126, 72 men, 54.9 ± 1.1 years old) during colonoscopy. Main Outcome Measurement Discomfort (visual analogue scale [VAS] pain score), anxiety (State-Trait Anxiety Inventory Form Y [STAI-Y] anxiety score), colonoscopy performance, adverse events, and recovery time. Results Precolonoscopy VAS pain and STAI-Y scores were comparable between the 2 groups. There were no differences between groups in (1) pain VAS or STAI Y-1 anxiety scores during or immediately after colonoscopy, (2) procedural success rate (Penthrox: 121/125 vs M&F: 124/126), (3) hypotension during colonoscopy (7/125 vs 8/126), (4) tachycardia (5/125 vs 3/126), (5) cecal arrival time (8 ± 1 vs 8 ± 1 minutes), or (6) polyp detection rate (30/125 vs 43/126). Additional intravenous sedation was required in 10 patients (8%) who received Penthrox. Patients receiving Penthrox alone had no desaturation (oxygen saturation [SaO2] < 90%) events (0/115 vs 5/126; P = .03), awoke quicker (3 ± 0 vs 19 ± 1 minutes; P < .001) and were ready for discharge earlier (37 ± 1 vs 66 ± 2 minutes; P < .001) than those receiving intravenous M&F. Limitations Inhaled Penthrox is not yet available in the United States and Europe. Conclusions Patient-controlled analgesia with inhaled Penthrox is feasible and as effective as conventional sedation for colonoscopy with shorter recovery time, is not associated with respiratory depression, and does not influence the procedural success and polyp detection. Inhaled methoxyflurane (Penthrox, Medical Device International, Melbourne, Australia) has been used extensively in Australasia (Australia and New Zealand) to manage trauma-related pain. The aim is to evaluate the efficacy, safety, and outcome of Penthrox for colonoscopy. Prospective randomized study. Three tertiary endoscopic centers. Two hundred fifty-one patients were randomized to receive either Penthrox (n = 125, 70 men, 51.4 ± 1.1 years old) or intravenous midazolam and fentanyl (M&F; n = 126, 72 men, 54.9 ± 1.1 years old) during colonoscopy. Discomfort (visual analogue scale [VAS] pain score), anxiety (State-Trait Anxiety Inventory Form Y [STAI-Y] anxiety score), colonoscopy performance, adverse events, and recovery time. Precolonoscopy VAS pain and STAI-Y scores were comparable between the 2 groups. There were no differences between groups in (1) pain VAS or STAI Y-1 anxiety scores during or immediately after colonoscopy, (2) procedural success rate (Penthrox: 121/125 vs M&F: 124/126), (3) hypotension during colonoscopy (7/125 vs 8/126), (4) tachycardia (5/125 vs 3/126), (5) cecal arrival time (8 ± 1 vs 8 ± 1 minutes), or (6) polyp detection rate (30/125 vs 43/126). Additional intravenous sedation was required in 10 patients (8%) who received Penthrox. Patients receiving Penthrox alone had no desaturation (oxygen saturation [SaO2] < 90%) events (0/115 vs 5/126; P = .03), awoke quicker (3 ± 0 vs 19 ± 1 minutes; P < .001) and were ready for discharge earlier (37 ± 1 vs 66 ± 2 minutes; P < .001) than those receiving intravenous M&F. Inhaled Penthrox is not yet available in the United States and Europe. Patient-controlled analgesia with inhaled Penthrox is feasible and as effective as conventional sedation for colonoscopy with shorter recovery time, is not associated with respiratory depression, and does not influence the procedural success and polyp detection." @default.
• W2038004015 created "2016-06-24" @default.
• W2038004015 creator A5019511628 @default.
• W2038004015 creator A5023533043 @default.
• W2038004015 creator A5030187765 @default.
• W2038004015 creator A5037991283 @default.
• W2038004015 creator A5064444666 @default.
• W2038004015 creator A5065389707 @default.
• W2038004015 creator A5072097130 @default.
• W2038004015 creator A5073463104 @default.
• W2038004015 creator A5075020675 @default.
• W2038004015 creator A5077161121 @default.
• W2038004015 creator A5090131012 @default.
• W2038004015 creator A5091899614 @default.
• W2038004015 date "2013-12-01" @default.
• W2038004015 modified "2023-10-17" @default.
• W2038004015 title "Patient-controlled analgesia with inhaled methoxyflurane versus conventional endoscopist-provided sedation for colonoscopy: a randomized multicenter trial" @default.
• W2038004015 cites W1720859419 @default.
• W2038004015 cites W181459764 @default.
• W2038004015 cites W1944368411 @default.
• W2038004015 cites W1972203577 @default.
• W2038004015 cites W1982431712 @default.
• W2038004015 cites W1993316528 @default.
• W2038004015 cites W2007209111 @default.
• W2038004015 cites W2008666723 @default.
• W2038004015 cites W2009780901 @default.
• W2038004015 cites W2015858299 @default.
• W2038004015 cites W2021867764 @default.
• W2038004015 cites W2023422228 @default.
• W2038004015 cites W2026506405 @default.
• W2038004015 cites W2035429460 @default.
• W2038004015 cites W2040081963 @default.
• W2038004015 cites W2043263816 @default.
• W2038004015 cites W2046908639 @default.
• W2038004015 cites W2050574819 @default.
• W2038004015 cites W2064766404 @default.
• W2038004015 cites W2074815694 @default.
• W2038004015 cites W2088719361 @default.
• W2038004015 cites W2091341100 @default.
• W2038004015 cites W2105033263 @default.
• W2038004015 cites W2110743316 @default.
• W2038004015 cites W2112911136 @default.
• W2038004015 cites W2112955500 @default.
• W2038004015 cites W2115454535 @default.
• W2038004015 cites W2115823456 @default.
• W2038004015 cites W2130543432 @default.
• W2038004015 cites W2144814927 @default.
• W2038004015 cites W2153344530 @default.
• W2038004015 cites W2153407324 @default.
• W2038004015 cites W2160927057 @default.
• W2038004015 cites W2170093274 @default.
• W2038004015 cites W2312454689 @default.
• W2038004015 cites W2319479948 @default.
• W2038004015 cites W4246967036 @default.
• W2038004015 doi "https://doi.org/10.1016/j.gie.2013.05.023" @default.
• W2038004015 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23810328" @default.
• W2038004015 hasPublicationYear "2013" @default.
• W2038004015 type Work @default.
• W2038004015 sameAs 2038004015 @default.
• W2038004015 citedByCount "31" @default.
• W2038004015 countsByYear W20380040152014 @default.
• W2038004015 countsByYear W20380040152015 @default.
• W2038004015 countsByYear W20380040152016 @default.
• W2038004015 countsByYear W20380040152018 @default.
• W2038004015 countsByYear W20380040152019 @default.
• W2038004015 countsByYear W20380040152020 @default.
• W2038004015 countsByYear W20380040152021 @default.
• W2038004015 countsByYear W20380040152022 @default.
• W2038004015 countsByYear W20380040152023 @default.
• W2038004015 crossrefType "journal-article" @default.
• W2038004015 hasAuthorship W2038004015A5019511628 @default.
• W2038004015 hasAuthorship W2038004015A5023533043 @default.
• W2038004015 hasAuthorship W2038004015A5030187765 @default.
• W2038004015 hasAuthorship W2038004015A5037991283 @default.
• W2038004015 hasAuthorship W2038004015A5064444666 @default.
• W2038004015 hasAuthorship W2038004015A5065389707 @default.
• W2038004015 hasAuthorship W2038004015A5072097130 @default.
• W2038004015 hasAuthorship W2038004015A5073463104 @default.
• W2038004015 hasAuthorship W2038004015A5075020675 @default.
• W2038004015 hasAuthorship W2038004015A5077161121 @default.
• W2038004015 hasAuthorship W2038004015A5090131012 @default.
• W2038004015 hasAuthorship W2038004015A5091899614 @default.
• W2038004015 hasConcept C118552586 @default.
• W2038004015 hasConcept C121608353 @default.
• W2038004015 hasConcept C126322002 @default.
• W2038004015 hasConcept C141071460 @default.
• W2038004015 hasConcept C14184104 @default.
• W2038004015 hasConcept C168563851 @default.
• W2038004015 hasConcept C197934379 @default.
• W2038004015 hasConcept C2776814716 @default.
• W2038004015 hasConcept C2778000748 @default.
• W2038004015 hasConcept C2778435480 @default.
• W2038004015 hasConcept C2781072394 @default.
• W2038004015 hasConcept C42219234 @default.
• W2038004015 hasConcept C526805850 @default.
• W2038004015 hasConcept C558461103 @default.
• W2038004015 hasConcept C71924100 @default.
• W2038004015 hasConceptScore W2038004015C118552586 @default.

• next