FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038007979> ?p ?o ?g. }

• W2038007979 endingPage "313" @default.
• W2038007979 startingPage "291" @default.
• W2038007979 abstract "1. We compared the pressure-response characteristics of C fibre and A fibre baroreceptors in the carotid sinus of anaesthetized dogs, recording impulses from the sinus nerve and varying mean pressure in the vascularly isolated sinus, which was distended with a pulsatile pressure. Functional stimulus-response curves were obtained by gradually increasing sinus pressure above and decreasing it below a set-point of 100 mmHg. Baroreceptors were identified by a pulsatile discharge synchronous with the pulsations in sinus pressure. A and C fibre baroreceptors were identified by the conduction velocities and blocking temperatures of their axons. 2. The pressure-response characteristics of C and A fibre baroreceptors differed in several respects. C fibres had a pulsatile firing threshold 50 mmHg higher than that of A fibres (105.8 +/- 1.8 and 54.6 +/- 2.9 mmHg, respectively), an average maximal sensitivity 35% of that of A fibres (0.39 and 1.12 impulses s-1 mmHg-1, respectively), and a maximal frequency (at 220 mmHg) 29% of that of A fibres (24.5 and 84.3 impulses/s, respectively). Although invariably pulsatile at pressures above threshold, the firing pattern of C fibre baroreceptors tended to be more irregular than that of their A fibre counterparts. 3. Impulses were also recorded from C fibres that were stimulated by increasing sinus pressure but had an irregular, non-pulsatile discharge, a high pressure threshold (averaging 154.1 +/- 7.2 mmHg), and a low maximum frequency (10.8 +/- 2.4 impulses/s). 4. Cooling the sinus nerve progressively attenuated conduction in both A and C fibres, A fibres being blocked between 12 and 4 degrees C (mean 6.8 degrees C) and C fibres between 4 and -1.5 degrees C (mean 1.0 degree C). Although cooling the sinus nerve to 7 degrees C did not block conduction in all A fibres, impulse activity in baroreceptor A fibres at a carotid sinus pressure of 200 mmHg was no greater than that at a pressure of 75 mmHg. By contrast, at 7 degrees C baroreceptor C fibres still provided a signal proportional to sinus pressure. 5. Our results suggest that A and C fibre baroreceptors subserve different reflex functions, the former signalling changes in arterial pressure both above and below the normal set-point, the latter only changes above. They also suggest that differential cold blockade may be a useful tool to determine the contribution of C fibre baroreceptors to cardiovascular reflexes." @default.
• W2038007979 created "2016-06-24" @default.
• W2038007979 creator A5046428906 @default.
• W2038007979 creator A5077858912 @default.
• W2038007979 creator A5085063600 @default.
• W2038007979 date "1987-12-01" @default.
• W2038007979 modified "2023-10-15" @default.
• W2038007979 title "Characteristics of C fibre baroreceptors in the carotid sinus of dogs." @default.
• W2038007979 cites W1582844561 @default.
• W2038007979 cites W1967492199 @default.
• W2038007979 cites W1981413880 @default.
• W2038007979 cites W2005055651 @default.
• W2038007979 cites W2005542886 @default.
• W2038007979 cites W2006964596 @default.
• W2038007979 cites W2013354919 @default.
• W2038007979 cites W2029216375 @default.
• W2038007979 cites W2033041795 @default.
• W2038007979 cites W2034297174 @default.
• W2038007979 cites W2049956535 @default.
• W2038007979 cites W2053239559 @default.
• W2038007979 cites W2058714782 @default.
• W2038007979 cites W2059552415 @default.
• W2038007979 cites W2073895783 @default.
• W2038007979 cites W2077638416 @default.
• W2038007979 cites W2086469358 @default.
• W2038007979 cites W2096451195 @default.
• W2038007979 cites W2114963959 @default.
• W2038007979 cites W2130115162 @default.
• W2038007979 cites W2132682553 @default.
• W2038007979 cites W2138343810 @default.
• W2038007979 cites W2157130983 @default.
• W2038007979 cites W2160534641 @default.
• W2038007979 cites W2170212888 @default.
• W2038007979 cites W2171738262 @default.
• W2038007979 cites W2233939162 @default.
• W2038007979 cites W4290447939 @default.
• W2038007979 doi "https://doi.org/10.1113/jphysiol.1987.sp016871" @default.
• W2038007979 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1191962" @default.
• W2038007979 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3443968" @default.
• W2038007979 hasPublicationYear "1987" @default.
• W2038007979 type Work @default.
• W2038007979 sameAs 2038007979 @default.
• W2038007979 citedByCount "45" @default.
• W2038007979 countsByYear W20380079792012 @default.
• W2038007979 countsByYear W20380079792013 @default.
• W2038007979 countsByYear W20380079792014 @default.
• W2038007979 countsByYear W20380079792016 @default.
• W2038007979 countsByYear W20380079792018 @default.
• W2038007979 countsByYear W20380079792023 @default.
• W2038007979 crossrefType "journal-article" @default.
• W2038007979 hasAuthorship W2038007979A5046428906 @default.
• W2038007979 hasAuthorship W2038007979A5077858912 @default.
• W2038007979 hasAuthorship W2038007979A5085063600 @default.
• W2038007979 hasBestOaLocation W20380079792 @default.
• W2038007979 hasConcept C105702510 @default.
• W2038007979 hasConcept C126322002 @default.
• W2038007979 hasConcept C136229726 @default.
• W2038007979 hasConcept C157369684 @default.
• W2038007979 hasConcept C164705383 @default.
• W2038007979 hasConcept C185592680 @default.
• W2038007979 hasConcept C192562407 @default.
• W2038007979 hasConcept C2776407911 @default.
• W2038007979 hasConcept C2777953023 @default.
• W2038007979 hasConcept C2778774071 @default.
• W2038007979 hasConcept C59822182 @default.
• W2038007979 hasConcept C71924100 @default.
• W2038007979 hasConcept C79191276 @default.
• W2038007979 hasConcept C79752029 @default.
• W2038007979 hasConcept C84393581 @default.
• W2038007979 hasConcept C86803240 @default.
• W2038007979 hasConceptScore W2038007979C105702510 @default.
• W2038007979 hasConceptScore W2038007979C126322002 @default.
• W2038007979 hasConceptScore W2038007979C136229726 @default.
• W2038007979 hasConceptScore W2038007979C157369684 @default.
• W2038007979 hasConceptScore W2038007979C164705383 @default.
• W2038007979 hasConceptScore W2038007979C185592680 @default.
• W2038007979 hasConceptScore W2038007979C192562407 @default.
• W2038007979 hasConceptScore W2038007979C2776407911 @default.
• W2038007979 hasConceptScore W2038007979C2777953023 @default.
• W2038007979 hasConceptScore W2038007979C2778774071 @default.
• W2038007979 hasConceptScore W2038007979C59822182 @default.
• W2038007979 hasConceptScore W2038007979C71924100 @default.
• W2038007979 hasConceptScore W2038007979C79191276 @default.
• W2038007979 hasConceptScore W2038007979C79752029 @default.
• W2038007979 hasConceptScore W2038007979C84393581 @default.
• W2038007979 hasConceptScore W2038007979C86803240 @default.
• W2038007979 hasIssue "1" @default.
• W2038007979 hasLocation W20380079791 @default.
• W2038007979 hasLocation W20380079792 @default.
• W2038007979 hasLocation W20380079793 @default.
• W2038007979 hasOpenAccess W2038007979 @default.
• W2038007979 hasPrimaryLocation W20380079791 @default.
• W2038007979 hasRelatedWork W1977638873 @default.
• W2038007979 hasRelatedWork W2068702275 @default.
• W2038007979 hasRelatedWork W2156701136 @default.
• W2038007979 hasRelatedWork W2171999802 @default.
• W2038007979 hasRelatedWork W2276310238 @default.
• W2038007979 hasRelatedWork W2282032720 @default.

• next