FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038021132> ?p ?o ?g. }

• W2038021132 endingPage "8" @default.
• W2038021132 startingPage "431" @default.
• W2038021132 abstract "Human nuclear proteins P1Mcm3 and P1Cdc46 have high sequence similarities with the corresponding yeast proteins known to be required for the initiation of genome replication. Nuclei of proliferating HeLa cells contain relatively high amounts of P1Mcm3 (about 10(6) molecules/nucleus) of which only a small fraction is bound to a nuclear structure, most probably chromatin. At 0.5 M NaCl, the structure-bound nuclear protein can be partially solubilized as a dimer composed of P1Mcm3 and the related protein P1Cdc46. However, most protein P1Mcm3 is not bound to a nuclear structure and appears in the nucleoplasm. About 10% of protein P1Mcm3 in the soluble fraction is free and uncomplexed, and the remaining P1Mcm3 forms stable complexes with protein P1Cdc46. These P1Mcm3/Cdc46 complexes occur as dimers and in high-molecular-mass complexes (approximately 500 kDa). The high-molecular-mass complexes dissociate in 0.5 M NaCl and release P1Mcm3/Cdc46 dimers. It has frequently been proposed that the Mcm proteins may function as licensing factors for genome replication. Our data imply that the active form of an Mcm protein is not a monomer, but a protein complex that includes an Mcm3/Cdc46 dimer. DNA polymerase alpha is not a component of this complex." @default.
• W2038021132 created "2016-06-24" @default.
• W2038021132 creator A5022961132 @default.
• W2038021132 creator A5026558056 @default.
• W2038021132 creator A5047770626 @default.
• W2038021132 creator A5056766308 @default.
• W2038021132 creator A5068717323 @default.
• W2038021132 creator A5089022614 @default.
• W2038021132 date "1995-03-01" @default.
• W2038021132 modified "2023-09-23" @default.
• W2038021132 title "Interactions of human nuclear proteins P1Mcm3 and P1Cdc46." @default.
• W2038021132 cites W1199670722 @default.
• W2038021132 cites W1419929824 @default.
• W2038021132 cites W1510322316 @default.
• W2038021132 cites W1963900436 @default.
• W2038021132 cites W1964429281 @default.
• W2038021132 cites W1979492674 @default.
• W2038021132 cites W1985973665 @default.
• W2038021132 cites W2026396830 @default.
• W2038021132 cites W2034811570 @default.
• W2038021132 cites W2041027497 @default.
• W2038021132 cites W2052881693 @default.
• W2038021132 cites W2059594509 @default.
• W2038021132 cites W2072897152 @default.
• W2038021132 cites W2087401860 @default.
• W2038021132 cites W2091038230 @default.
• W2038021132 cites W2092220124 @default.
• W2038021132 cites W2100837269 @default.
• W2038021132 cites W2101108802 @default.
• W2038021132 cites W2107372552 @default.
• W2038021132 cites W2144042585 @default.
• W2038021132 cites W2144892831 @default.
• W2038021132 cites W2159268545 @default.
• W2038021132 cites W2220955715 @default.
• W2038021132 cites W2271067653 @default.
• W2038021132 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7705359" @default.
• W2038021132 hasPublicationYear "1995" @default.
• W2038021132 type Work @default.
• W2038021132 sameAs 2038021132 @default.
• W2038021132 citedByCount "51" @default.
• W2038021132 countsByYear W20380211322012 @default.
• W2038021132 countsByYear W20380211322013 @default.
• W2038021132 countsByYear W20380211322014 @default.
• W2038021132 countsByYear W20380211322015 @default.
• W2038021132 countsByYear W20380211322016 @default.
• W2038021132 countsByYear W20380211322017 @default.
• W2038021132 countsByYear W20380211322018 @default.
• W2038021132 countsByYear W20380211322019 @default.
• W2038021132 countsByYear W20380211322020 @default.
• W2038021132 countsByYear W20380211322023 @default.
• W2038021132 crossrefType "journal-article" @default.
• W2038021132 hasAuthorship W2038021132A5022961132 @default.
• W2038021132 hasAuthorship W2038021132A5026558056 @default.
• W2038021132 hasAuthorship W2038021132A5047770626 @default.
• W2038021132 hasAuthorship W2038021132A5056766308 @default.
• W2038021132 hasAuthorship W2038021132A5068717323 @default.
• W2038021132 hasAuthorship W2038021132A5089022614 @default.
• W2038021132 hasConcept C104317684 @default.
• W2038021132 hasConcept C112952253 @default.
• W2038021132 hasConcept C178790620 @default.
• W2038021132 hasConcept C181199279 @default.
• W2038021132 hasConcept C183873130 @default.
• W2038021132 hasConcept C185592680 @default.
• W2038021132 hasConcept C188036394 @default.
• W2038021132 hasConcept C190062978 @default.
• W2038021132 hasConcept C2779546866 @default.
• W2038021132 hasConcept C29512474 @default.
• W2038021132 hasConcept C552990157 @default.
• W2038021132 hasConcept C55493867 @default.
• W2038021132 hasConcept C58121356 @default.
• W2038021132 hasConcept C73573662 @default.
• W2038021132 hasConcept C83640560 @default.
• W2038021132 hasConcept C86339819 @default.
• W2038021132 hasConcept C86803240 @default.
• W2038021132 hasConcept C94912109 @default.
• W2038021132 hasConcept C98086919 @default.
• W2038021132 hasConceptScore W2038021132C104317684 @default.
• W2038021132 hasConceptScore W2038021132C112952253 @default.
• W2038021132 hasConceptScore W2038021132C178790620 @default.
• W2038021132 hasConceptScore W2038021132C181199279 @default.
• W2038021132 hasConceptScore W2038021132C183873130 @default.
• W2038021132 hasConceptScore W2038021132C185592680 @default.
• W2038021132 hasConceptScore W2038021132C188036394 @default.
• W2038021132 hasConceptScore W2038021132C190062978 @default.
• W2038021132 hasConceptScore W2038021132C2779546866 @default.
• W2038021132 hasConceptScore W2038021132C29512474 @default.
• W2038021132 hasConceptScore W2038021132C552990157 @default.
• W2038021132 hasConceptScore W2038021132C55493867 @default.
• W2038021132 hasConceptScore W2038021132C58121356 @default.
• W2038021132 hasConceptScore W2038021132C73573662 @default.
• W2038021132 hasConceptScore W2038021132C83640560 @default.
• W2038021132 hasConceptScore W2038021132C86339819 @default.
• W2038021132 hasConceptScore W2038021132C86803240 @default.
• W2038021132 hasConceptScore W2038021132C94912109 @default.
• W2038021132 hasConceptScore W2038021132C98086919 @default.
• W2038021132 hasIssue "2" @default.
• W2038021132 hasLocation W20380211321 @default.
• W2038021132 hasOpenAccess W2038021132 @default.

• next