FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038082227> ?p ?o ?g. }

• W2038082227 endingPage "4077" @default.
• W2038082227 startingPage "4068" @default.
• W2038082227 abstract "Mammalian cells respond to their substrates by complex changes in gene expression profiles, morphology, proliferation and migration. We report that substrate nanotopography alters morpohology and proliferation of human embryonic stem cells (hESCs). Fibronectin-coated poly(di-methyl siloxane) substrates with line-grating (600 nm ridges with 600 nm spacing and 600±150 nm feature height) induced hESC alignment and elongation, mediated the organization of cytoskeletal components including actin, vimentin, and α-tubulin, and reduced proliferation. Spatial polarization of gamma-tubulin complexes was also observed in response to nanotopography. Furthermore, the addition of actin disrupting agents attenuated the alignment and proliferative effects of nanotopography. These findings further demonstrate the importance of interplay between cytoskeleton and substrate interactions as a key modulator of morphological and proliferative cellular response in hESCs on nanotopography." @default.
• W2038082227 created "2016-06-24" @default.
• W2038082227 creator A5019329595 @default.
• W2038082227 creator A5042597057 @default.
• W2038082227 creator A5044928451 @default.
• W2038082227 creator A5052258825 @default.
• W2038082227 creator A5058092099 @default.
• W2038082227 creator A5086624192 @default.
• W2038082227 date "2007-10-01" @default.
• W2038082227 modified "2023-10-12" @default.
• W2038082227 title "The effect of actin disrupting agents on contact guidance of human embryonic stem cells" @default.
• W2038082227 cites W1590619267 @default.
• W2038082227 cites W1603508604 @default.
• W2038082227 cites W1854871441 @default.
• W2038082227 cites W1963892111 @default.
• W2038082227 cites W1964413664 @default.
• W2038082227 cites W1972081276 @default.
• W2038082227 cites W1976977538 @default.
• W2038082227 cites W1979522094 @default.
• W2038082227 cites W1992363704 @default.
• W2038082227 cites W1994538451 @default.
• W2038082227 cites W2001991657 @default.
• W2038082227 cites W2006805259 @default.
• W2038082227 cites W2008079151 @default.
• W2038082227 cites W2008681436 @default.
• W2038082227 cites W2016081742 @default.
• W2038082227 cites W2021434165 @default.
• W2038082227 cites W2023979914 @default.
• W2038082227 cites W2032420735 @default.
• W2038082227 cites W2034984922 @default.
• W2038082227 cites W2042464350 @default.
• W2038082227 cites W2050354346 @default.
• W2038082227 cites W2059717168 @default.
• W2038082227 cites W2060250773 @default.
• W2038082227 cites W2067121924 @default.
• W2038082227 cites W2084936639 @default.
• W2038082227 cites W2086943348 @default.
• W2038082227 cites W2091076029 @default.
• W2038082227 cites W2096791952 @default.
• W2038082227 cites W2103240277 @default.
• W2038082227 cites W2113641476 @default.
• W2038082227 cites W2144023435 @default.
• W2038082227 cites W2150214660 @default.
• W2038082227 cites W2157388755 @default.
• W2038082227 cites W2158200659 @default.
• W2038082227 cites W2433582314 @default.
• W2038082227 doi "https://doi.org/10.1016/j.biomaterials.2007.05.027" @default.
• W2038082227 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2257875" @default.
• W2038082227 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17576011" @default.
• W2038082227 hasPublicationYear "2007" @default.
• W2038082227 type Work @default.
• W2038082227 sameAs 2038082227 @default.
• W2038082227 citedByCount "207" @default.
• W2038082227 countsByYear W20380822272012 @default.
• W2038082227 countsByYear W20380822272013 @default.
• W2038082227 countsByYear W20380822272014 @default.
• W2038082227 countsByYear W20380822272015 @default.
• W2038082227 countsByYear W20380822272016 @default.
• W2038082227 countsByYear W20380822272017 @default.
• W2038082227 countsByYear W20380822272018 @default.
• W2038082227 countsByYear W20380822272019 @default.
• W2038082227 countsByYear W20380822272020 @default.
• W2038082227 countsByYear W20380822272021 @default.
• W2038082227 countsByYear W20380822272022 @default.
• W2038082227 countsByYear W20380822272023 @default.
• W2038082227 crossrefType "journal-article" @default.
• W2038082227 hasAuthorship W2038082227A5019329595 @default.
• W2038082227 hasAuthorship W2038082227A5042597057 @default.
• W2038082227 hasAuthorship W2038082227A5044928451 @default.
• W2038082227 hasAuthorship W2038082227A5052258825 @default.
• W2038082227 hasAuthorship W2038082227A5058092099 @default.
• W2038082227 hasAuthorship W2038082227A5086624192 @default.
• W2038082227 hasBestOaLocation W20380822272 @default.
• W2038082227 hasConcept C104317684 @default.
• W2038082227 hasConcept C12554922 @default.
• W2038082227 hasConcept C125705527 @default.
• W2038082227 hasConcept C142669718 @default.
• W2038082227 hasConcept C145103041 @default.
• W2038082227 hasConcept C147447768 @default.
• W2038082227 hasConcept C1491633281 @default.
• W2038082227 hasConcept C189165786 @default.
• W2038082227 hasConcept C192562407 @default.
• W2038082227 hasConcept C203014093 @default.
• W2038082227 hasConcept C204232928 @default.
• W2038082227 hasConcept C2777803738 @default.
• W2038082227 hasConcept C28328180 @default.
• W2038082227 hasConcept C2993400109 @default.
• W2038082227 hasConcept C55493867 @default.
• W2038082227 hasConcept C86492073 @default.
• W2038082227 hasConcept C86803240 @default.
• W2038082227 hasConcept C95444343 @default.
• W2038082227 hasConceptScore W2038082227C104317684 @default.
• W2038082227 hasConceptScore W2038082227C12554922 @default.
• W2038082227 hasConceptScore W2038082227C125705527 @default.
• W2038082227 hasConceptScore W2038082227C142669718 @default.
• W2038082227 hasConceptScore W2038082227C145103041 @default.
• W2038082227 hasConceptScore W2038082227C147447768 @default.
• W2038082227 hasConceptScore W2038082227C1491633281 @default.

• next