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- W2038086188 abstract "The combination of a rising incidence and a poor survival rate makes oesophageal cancer a major health issue. Adenocarcinoma of the oesophagus is associated with one of the commonest pre-malignant lesions recognised, Barrett’s metaplasia. This provides a focus for early detection and intervention. The subjects of acid suppression, bile reflux, COX-2 inhibition and ablation therapy will be discussed herewith. Established carcinoma is now rarely treated by surgery alone and this review discusses the benefits of multimodality therapy combined with more accurate staging techniques. Finally an emerging understanding of the molecular events that characterise the transition to carcinoma may provide novel targets in cancer therapy such as epidermal growth factor receptor (EGFR) and TNF-α. This review will focus on some of the future developments in the treatment of oesophageal cancer." @default.
- W2038086188 created "2016-06-24" @default.
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- W2038086188 creator A5091382015 @default.
- W2038086188 date "2001-11-01" @default.
- W2038086188 modified "2023-09-26" @default.
- W2038086188 title "The treatment, management and prevention of oesophageal cancer" @default.
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- W2038086188 doi "https://doi.org/10.1517/14712598.1.6.1017" @default.
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