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- W2038164834 abstract "Graded doses of zinc sulphate (injected i.p. 72 and 48 h before sacrifice) reduced gastric glandular ulceration, inhibited mast cell degranulation in the mucosa and submucosa of the glandular stomach wall, and raised the serum and stomach zinc levels in rats given reserpine (5 mg/kg, i.p.) 18 h before sacrifice. All these effects were dose-dependent. The minimum doses showing significant effects (antiulcer, 1.4 mg/kg; inhibition of mast cell degranulation, 5.5 mg/kg; serum and stomach zinc, 0.7 mg/kg) suggest that the antiulcer action of zinc sulphate is not entirely due to prevention of mast cell degranulation in this ulcer model." @default.
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- W2038164834 date "1978-04-01" @default.
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- W2038164834 title "Observations on the influence of graded pretreatment doses of zinc sulphate on the gastric effects of reserpine in rats" @default.
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- W2038164834 doi "https://doi.org/10.1016/s0031-6989(78)80027-7" @default.
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