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- W2038202398 abstract "Risperidone is a widely used agent as first-line treatment in schizophrenia with a favorable side-effect profile. However, a number of case reports have suggested an increase in obsessive-compulsive symptoms in patients treated with risperidone.The aim of this study was to investigate the effect of risperidone on obsessive-compulsive symptoms in the treatment of schizophrenia.Forty patients with DSM-IV diagnosis of schizophrenia were included in the study. The Yale-Brown obsessive compulsive scale was administered before, at the end of first and second months of treatment. Paired-samples t-test was used to compare the three assessments.There was not an increase, but a significant decrease, in YBOCS scores over time during risperidone treatment (p<0.05).In the present study risperidone caused a significant decrease in obsessive-compulsive symptoms in the treatment of schizophrenia." @default.
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- W2038202398 date "2003-01-01" @default.
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- W2038202398 title "Reduced short-term obsessive-compulsive symptoms in schizophrenic patients treated with risperidone: a single-blind prospective study" @default.
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- W2038202398 doi "https://doi.org/10.1002/hup.536" @default.
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