FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038204033> ?p ?o ?g. }

• W2038204033 endingPage "e20513" @default.
• W2038204033 startingPage "e20513" @default.
• W2038204033 abstract "Cuticle renewal is a complex biological process that depends on the cross talk between hormone levels and gene expression. This study characterized the expression of two genes encoding cuticle proteins sharing the four conserved amino acid blocks of the Tweedle family, AmelTwdl1 and AmelTwdl2, and a gene encoding a cuticle peroxidase containing the Animal haem peroxidase domain, Ampxd, in the honey bee. Gene sequencing and annotation validated the formerly predicted tweedle genes, and revealed a novel gene, Ampxd, in the honey bee genome. Expression of these genes was studied in the context of the ecdysteroid-coordinated pupal-to-adult molt, and in different tissues. Higher transcript levels were detected in the integument after the ecdysteroid peak that induces apolysis, coinciding with the synthesis and deposition of the adult exoskeleton and its early differentiation. The effect of this hormone was confirmed in vivo by tying a ligature between the thorax and abdomen of early pupae to prevent the abdominal integument from coming in contact with ecdysteroids released from the prothoracic gland. This procedure impaired the natural increase in transcript levels in the abdominal integument. Both tweedle genes were expressed at higher levels in the empty gut than in the thoracic integument and trachea of pharate adults. In contrast, Ampxd transcripts were found in higher levels in the thoracic integument and trachea than in the gut. Together, the data strongly suggest that these three genes play roles in ecdysteroid-dependent exoskeleton construction and differentiation and also point to a possible role for the two tweedle genes in the formation of the cuticle (peritrophic membrane) that internally lines the gut." @default.
• W2038204033 created "2016-06-24" @default.
• W2038204033 creator A5011624590 @default.
• W2038204033 creator A5022674796 @default.
• W2038204033 creator A5035489445 @default.
• W2038204033 creator A5062657086 @default.
• W2038204033 creator A5065196233 @default.
• W2038204033 creator A5071566036 @default.
• W2038204033 date "2011-05-31" @default.
• W2038204033 modified "2023-09-27" @default.
• W2038204033 title "Ecdysteroid-Dependent Expression of the Tweedle and Peroxidase Genes during Adult Cuticle Formation in the Honey Bee, Apis mellifera" @default.
• W2038204033 cites W1569378052 @default.
• W2038204033 cites W1573267684 @default.
• W2038204033 cites W1625829991 @default.
• W2038204033 cites W1634871183 @default.
• W2038204033 cites W1973309364 @default.
• W2038204033 cites W1973393227 @default.
• W2038204033 cites W1977665189 @default.
• W2038204033 cites W1978852670 @default.
• W2038204033 cites W1979276944 @default.
• W2038204033 cites W1981939829 @default.
• W2038204033 cites W1982053542 @default.
• W2038204033 cites W1984691048 @default.
• W2038204033 cites W1985355920 @default.
• W2038204033 cites W1985835787 @default.
• W2038204033 cites W1986343037 @default.
• W2038204033 cites W1988860493 @default.
• W2038204033 cites W1992018680 @default.
• W2038204033 cites W1992365463 @default.
• W2038204033 cites W1993387760 @default.
• W2038204033 cites W2002706767 @default.
• W2038204033 cites W2006010856 @default.
• W2038204033 cites W2007480067 @default.
• W2038204033 cites W2017318459 @default.
• W2038204033 cites W2019125169 @default.
• W2038204033 cites W2030170025 @default.
• W2038204033 cites W2032353084 @default.
• W2038204033 cites W2045711286 @default.
• W2038204033 cites W2049973401 @default.
• W2038204033 cites W2057886743 @default.
• W2038204033 cites W2067205163 @default.
• W2038204033 cites W2068335520 @default.
• W2038204033 cites W2072525314 @default.
• W2038204033 cites W2073037174 @default.
• W2038204033 cites W2073567437 @default.
• W2038204033 cites W2074024123 @default.
• W2038204033 cites W2078813514 @default.
• W2038204033 cites W2080406023 @default.
• W2038204033 cites W2081392937 @default.
• W2038204033 cites W2085826131 @default.
• W2038204033 cites W2090787113 @default.
• W2038204033 cites W2097233732 @default.
• W2038204033 cites W2097567855 @default.
• W2038204033 cites W2100837269 @default.
• W2038204033 cites W2101108802 @default.
• W2038204033 cites W2102749897 @default.
• W2038204033 cites W2107277218 @default.
• W2038204033 cites W2117999210 @default.
• W2038204033 cites W2131796587 @default.
• W2038204033 cites W2133405889 @default.
• W2038204033 cites W2147996930 @default.
• W2038204033 cites W2157228103 @default.
• W2038204033 cites W2170488656 @default.
• W2038204033 cites W2171081570 @default.
• W2038204033 cites W2174964781 @default.
• W2038204033 cites W4232534952 @default.
• W2038204033 doi "https://doi.org/10.1371/journal.pone.0020513" @default.
• W2038204033 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3105072" @default.
• W2038204033 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21655217" @default.
• W2038204033 hasPublicationYear "2011" @default.
• W2038204033 type Work @default.
• W2038204033 sameAs 2038204033 @default.
• W2038204033 citedByCount "32" @default.
• W2038204033 countsByYear W20382040332013 @default.
• W2038204033 countsByYear W20382040332014 @default.
• W2038204033 countsByYear W20382040332015 @default.
• W2038204033 countsByYear W20382040332016 @default.
• W2038204033 countsByYear W20382040332017 @default.
• W2038204033 countsByYear W20382040332018 @default.
• W2038204033 countsByYear W20382040332019 @default.
• W2038204033 countsByYear W20382040332020 @default.
• W2038204033 countsByYear W20382040332021 @default.
• W2038204033 countsByYear W20382040332022 @default.
• W2038204033 countsByYear W20382040332023 @default.
• W2038204033 crossrefType "journal-article" @default.
• W2038204033 hasAuthorship W2038204033A5011624590 @default.
• W2038204033 hasAuthorship W2038204033A5022674796 @default.
• W2038204033 hasAuthorship W2038204033A5035489445 @default.
• W2038204033 hasAuthorship W2038204033A5062657086 @default.
• W2038204033 hasAuthorship W2038204033A5065196233 @default.
• W2038204033 hasAuthorship W2038204033A5071566036 @default.
• W2038204033 hasBestOaLocation W20382040331 @default.
• W2038204033 hasConcept C104317684 @default.
• W2038204033 hasConcept C105702510 @default.
• W2038204033 hasConcept C134018914 @default.
• W2038204033 hasConcept C136203487 @default.
• W2038204033 hasConcept C2776905768 @default.
• W2038204033 hasConcept C30055919 @default.

• next